A comparative study of thai and Australian crocodile bone for use as a potential biomaterial

Lewis, K; Boonyang, U; Evans, L; Siripaisarnpipat, S; Ben-Nissan, B

A comparative study of thai and Australian crocodile bone for use as a potential biomaterial

Lewis, K Boonyang, U Evans, L

Siripaisarnpipat, S Ben-Nissan, B

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Publication Type:: Journal Article
Citation:: Key Engineering Materials, 2006, 309-311 I pp. 15 - 18
Issue Date:: 2006-04-05

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Field	Value	Language
dc.contributor.author	Lewis, K	en_US
dc.contributor.author	Boonyang, U	en_US
dc.contributor.author	Evans, L https://orcid.org/0000-0003-1544-6868	en_US
dc.contributor.author	Siripaisarnpipat, S	en_US
dc.contributor.author	Ben-Nissan, B	en_US
dc.date.issued	2006-04-05	en_US
dc.identifier.citation	Key Engineering Materials, 2006, 309-311 I pp. 15 - 18	en_US
dc.identifier.issn	1013-9826	en_US
dc.identifier.uri	http://hdl.handle.net/10453/1133
dc.description.abstract	This study aims to characterize the structure and properties of crocodile bone to assess the potential for use in biomedical applications. Crocodile bone samples obtained from Thailand (Crocodylus siamensis) and Australia (Crocodylus porosus), being the tail and the tibia respectively, were treated to remove organic material and the inner spongy (trabecular) material. The dense cortical bone was used for comparative instrumental analyses. Specific comparisons were made against bovine cortical bone and pure synthetic hydroxyapatite. The material was then analyzed using simultaneous differential thermal analysis/thermogravimetric analysis (DTA/TGA), Fourier-Transform infrared spectroscopy (FTIR), and X-ray diffraction analysis (XRD). Imaging of full bone samples was also conducted using an environmental scanning electron microscopy (ESEM). The SEM provided valuable information through the imaging of samples, showing a marked increase in bone porosity for crocodile material when compared to bovine samples. The crystallinity and/or crystallite size of carbonated hydroxyapatite has been found to be lower than synthetic apatite, with the tibia being the least crystalline of the bone types studied. The crystallinity index (CI) is used as a measure of crystallite size and internal strain. The strain is affected by substitutions in the structure and these results provide a starting point for comparison of the resulting mechanical properties. There is a need for any biomaterial chosen for bone replacement to allow adequate osteointegration. Thus the study this far shows that crocodile bone is a very promising source of carbonated apatite for biomedical applications.	en_US
dc.relation.ispartof	Key Engineering Materials	en_US
dc.subject.classification	Materials	en_US
dc.title	A comparative study of thai and Australian crocodile bone for use as a potential biomaterial	en_US
dc.type	Journal Article
utslib.citation.volume	309-311 I	en_US
utslib.for	0999 Other Engineering	en_US
utslib.for	09 Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
utslib.copyright.status	closed_access
pubs.publication-status	Published	en_US
pubs.volume	309-311 I	en_US

Abstract:

This study aims to characterize the structure and properties of crocodile bone to assess the potential for use in biomedical applications. Crocodile bone samples obtained from Thailand (Crocodylus siamensis) and Australia (Crocodylus porosus), being the tail and the tibia respectively, were treated to remove organic material and the inner spongy (trabecular) material. The dense cortical bone was used for comparative instrumental analyses. Specific comparisons were made against bovine cortical bone and pure synthetic hydroxyapatite. The material was then analyzed using simultaneous differential thermal analysis/thermogravimetric analysis (DTA/TGA), Fourier-Transform infrared spectroscopy (FTIR), and X-ray diffraction analysis (XRD). Imaging of full bone samples was also conducted using an environmental scanning electron microscopy (ESEM). The SEM provided valuable information through the imaging of samples, showing a marked increase in bone porosity for crocodile material when compared to bovine samples. The crystallinity and/or crystallite size of carbonated hydroxyapatite has been found to be lower than synthetic apatite, with the tibia being the least crystalline of the bone types studied. The crystallinity index (CI) is used as a measure of crystallite size and internal strain. The strain is affected by substitutions in the structure and these results provide a starting point for comparison of the resulting mechanical properties. There is a need for any biomaterial chosen for bone replacement to allow adequate osteointegration. Thus the study this far shows that crocodile bone is a very promising source of carbonated apatite for biomedical applications.

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http://hdl.handle.net/10453/1133