School of Mathematical and Physical Sciences

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It's all relative: A multi-generational study using ForenSeq™ Kintelligence.

Daniel, R Raymond, J Sears, A Stock, A Scudder, N Padmabandu, G Kumar, SA Snedecor, J Antunes, J Hartman, D

The successful application of Forensic Investigative Genetic Genealogy (FIGG) to the identification of unidentified human remains and perpetrators of serious crime has led to a growing interest in ...

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Diverse Communities of Endemic and Cosmopolitan Lineages at Local Sites in the Lecanora polytropa Aggregate (Ascomycota)

Woodhouse, J Perez-Ortega, S Roux, C Bertrand, M Leavitt, SD

Recent work has suggested exceptional species-level diversity in the lichen-forming Lecanora polytropa complex (Lecanoraceae, Ascomycota). However, biogeographic patterns and the spatial st...

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CSF neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in FIRES and other infection-triggered encephalopathy syndromes.

Dale, RC Thomas, T Patel, S Han, VX Kothur, K Troedson, C Gupta, S Gill, D Malone, S Waak, M Calvert, S Subramanian, G Andrews, PI Kandula, T Menezes, MP Ardern-Holmes, S Mohammad, S Bandodkar, S Yan, J

OBJECTIVE: Infection-triggered encephalopathy syndromes (ITES) are potentially devastating neuroinflammatory conditions. Although some ITES syndromes have recognisable MRI neuroimaging phenotypes, ...

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Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids.

Yan, J Kothur, K Innes, EA Han, VX Jones, HF Patel, S Tsang, E Webster, R Gupta, S Troedson, C Menezes, MP Antony, J Ardern-Holmes, S Tantsis, E Mohammad, S Wienholt, L Pires, AS Heng, B Guillemin, GJ Guller, A Gill, D Bandodkar, S Dale, RC

BACKGROUND: Epileptic (previously infantile) spasms is the most common epileptic encephalopathy occurring during infancy and is frequently associated with abnormal neurodevelopmental outcomes. Epil...

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Acute encephalopathy with biphasic seizures and restricted diffusion.

Nguyen, KL McGurty, D Innes, EA Goetti, R Thomas, T Dal, S Bandodkar, S Yan, J Wong, M Dale, RC Mohammad, SS

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Development of a translational inflammation panel for the quantification of cerebrospinal fluid Pterin, Tryptophan-Kynurenine and Nitric oxide pathway metabolites.

Yan, J Han, VX Heng, B Guillemin, GJ Bandodkar, S Dale, RC

BACKGROUND: Neuroinflammatory diseases such as encephalitis, meningitis, multiple sclerosis and other neurological diseases with inflammatory components, have demonstrated a need for diagnostic bio...

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CSF neopterin, quinolinic acid and kynurenine/tryptophan ratio are biomarkers of active neuroinflammation.

Yan, J Kothur, K Mohammad, S Chung, J Patel, S Jones, HF Keating, BA Han, VX Webster, R Ardern-Holmes, S Antony, J Menezes, MP Tantsis, E Gill, D Gupta, S Kandula, T Sampaio, H Farrar, MA Troedson, C Andrews, PI Pillai, SC Heng, B Guillemin, GJ Guller, A Bandodkar, S Dale, RC

BACKGROUND: Defining the presence of acute and chronic brain inflammation remains a challenge to clinicians due to the heterogeneity of clinical presentations and aetiologies. However, defining the...

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The Risk of Pathogens Associated with Seed Potatoes (Solanum tuberosum) Imported to Sri Lanka : A Metagenomic Approach

Rajapaksha, RWPM Attanayaka, DPSTG Vivehananthan, K Linacre, A McNevin, D

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Profiling age and body fluid DNA methylation markers using nanopore adaptive sampling

Yuen, ZW-S Shanmuganandam, S Stanley, M Jiang, S Hein, N Daniel, R McNevin, D Jack, C Eyras, E

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Comparison of Likelihood Ratios from Probabilistic Genotyping for Two-Person Mixtures across Different Assays and Instruments

McNevin, D Barash, M

Continuous probabilistic genotyping (PG) provides a means to estimate the probative value of DNA mixtures tendered as evidence in court and subject to alternative propositions about the con...

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