Activity of pyocin S2 against Pseudomonas aeruginosa biofilms.

Publication Type:
Journal Article
Citation:
Antimicrobial agents and chemotherapy, 2012, 56 (3), pp. 1599 - 1601
Issue Date:
2012-03
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In cystic fibrosis patients, chronic lung infection with Pseudomonas aeruginosa and the associated decline in lung function are the major cause of mortality. In this report, we show that pyocin S2 displays potent activity against P. aeruginosa biofilms, thus representing a potentially improved therapeutic option. Using an invertebrate model of P. aeruginosa infection, we also show that pyocin S2 is highly active in vivo.
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