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Exfoliated kidney cells from urine for non-invasive kidney transplant monitoring: A potential opportunity?

Wu, HHL Parthiban, NK Goldys, EM Pollock, CA Saad, S

Kidney transplantation is usually the optimal treatment option for patients living with kidney failure given its associations with improved survival, quality of life outcomes and a reduction in the...

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Buscogeny: A BUSCO leveraged phylogenomic tree builder.

Webster, J Chapman, TA

Accurately resolving evolutionary relationships among organisms is a cornerstone of evolutionary biology, with phylogenetic trees serving as critical tools for this purpose. While single-gene phylo...

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Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry.

Zhang, C Michael, JA Teo, JD Song, H Westerhausen, MT Mutuku, SM Ellis, SR Don, AS

Myelin is the lipid-rich membrane that surrounds neuronal axons and is essential for neurological function in vertebrates. The development of therapeutics that stimulate myelin repair to treat demy...

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Deterministic and efficient source of frequency-polarization hyper-encoded photonic qubits

Coste, N Fioretto, DA Thomas, SE Wein, SC Ollivier, H Maillette de Buy Wenniger, I Henry, A Belabas, N Harouri, A Lemaitre, A Sagnes, I Somaschi, N Krebs, O Lanco, L Senellart, P

The frequency or color of photons is an attractive degree of freedom to encode and distribute quantum information over long distances. However, the generation of frequency-encoded photonic qubits h...

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Log-transformed approaches to variance estimation using auxiliary data

Singh, P Sharma, P Singh, A Zaman, T Emam, W

Reliable statistical inference requires accurate population variance estimate, especially in domains where measurement limitations and intrinsic variability impact data. Applying traditional estima...

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Characterizing ECOPD Phenotypes: Associations with In-Hospital Outcomes and Immunoinflammatory Mechanisms.

Wang, Q Wang, L Zhang, L Zhao, C Liu, Y Liu, L Yuan, L Feng, M Wang, G Li, L Zhang, S Yuan, Y Kang, D Zhang, X

BACKGROUND: Hospitalization due to exacerbations of chronic obstructive pulmonary disease (ECOPD) is linked to substantial mortality rates. OBJECTIVE: This study aimed to identify the clinical and ...

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AORI-HAP: a multidimensional risk index to predict in-hospital adverse outcomes in asthma exacerbations.

Yuan, L Zhao, C Wang, L Zhang, L Liu, Y Liu, L Feng, M Melén, E Wang, G Zhang, S Yuan, Y Wang, Q Li, Y Kang, D Zhang, X

BACKGROUND: Despite therapeutic advancements, asthma exacerbations (AEs) remain a major clinical challenge, with immune-inflammatory patterns incompletely characterized. Current guidelines lack rob...

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Indigenous peoples’ voices and engagement on climate change: towards improved health and wellbeing

Lansbury, N Mosby, V Creamer, SJ Moggridge, B Evans, GR Pecl, G Ireland, L

Western climate science largely fails to value, engage with and apply Indigenous Knowledges in a meaningful way. Here, we explore the ways in which the current gap in Indigenous Knowledges and repr...

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Prior exposure strongly influences mechanisms underpinning survival of heat shock in Escherichia coli

Yasir, M Turner, AK Bastkowski, S Jarvis, CS Sweet, R Truong, M Charles, IG Webber, MA

The heat shock response of i Escherichia coli /i represents a canonical example of how bacteria can recognize a stress and invoke a protective response by altering specific gene regulation. However...

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Applications of halophilic enzymes in the pharmaceutical industry and medicine

Velankar, R Shinde, V Kothari, M Gunjal, A

Halophiles are an important group of microorganisms that can grow under high salt conditions. The paper here describes the enzymes of halophiles and their mode of action. The application of halophi...

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