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The immune-modulatory potential of helminth-derived proteins in cellular models of inflammation: a systematic review with cross-study quantitative data analysis.

Stucke, S Feeney, A Lalor, R Donnelly, S Dalton, JP McKernan, D Dowd, E

Helminths are parasitic worms that secrete a plethora of immune regulatory molecules which allow them to moderate inflammatory responses by their host's immune system to ensure their survival withi...

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Exfoliated kidney cells from urine for non-invasive kidney transplant monitoring: A potential opportunity?

Wu, HHL Parthiban, NK Goldys, EM Pollock, CA Saad, S

Kidney transplantation is usually the optimal treatment option for patients living with kidney failure given its associations with improved survival, quality of life outcomes and a reduction in the...

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Buscogeny: A BUSCO leveraged phylogenomic tree builder.

Webster, J Chapman, TA

Accurately resolving evolutionary relationships among organisms is a cornerstone of evolutionary biology, with phylogenetic trees serving as critical tools for this purpose. While single-gene phylo...

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Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry.

Zhang, C Michael, JA Teo, JD Song, H Westerhausen, MT Mutuku, SM Ellis, SR Don, AS

Myelin is the lipid-rich membrane that surrounds neuronal axons and is essential for neurological function in vertebrates. The development of therapeutics that stimulate myelin repair to treat demy...

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Phylogenomics and the evolution of larval feeding habits in the blow flies (Diptera: Calliphoridae)

Beza-Beza, CF Soghigian, J Bailey, E Johnston, NP Cassel, BK Bayless, KM Wells, JD Yeates, DK Wallman, JF Yan, L Thomas-Cabianca, A Hickner, PV Grzywacz, A Meiklejohn, KA Torres, TT Scott, MJ Mikaelyan, A Zhang, D Cerretti, P Szpila, K Pape, T Wiegmann, BM

Blow flies (Diptera: Calliphoridae) occur worldwide and exhibit a wide range of larval feeding habits, including saprophagy, coprophagy, parasitism and predation. Understanding their biology is cri...

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Deterministic and efficient source of frequency-polarization hyper-encoded photonic qubits

Coste, N Fioretto, DA Thomas, SE Wein, SC Ollivier, H Maillette de Buy Wenniger, I Henry, A Belabas, N Harouri, A Lemaitre, A Sagnes, I Somaschi, N Krebs, O Lanco, L Senellart, P

The frequency or color of photons is an attractive degree of freedom to encode and distribute quantum information over long distances. However, the generation of frequency-encoded photonic qubits h...

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Log-transformed approaches to variance estimation using auxiliary data

Singh, P Sharma, P Singh, A Zaman, T Emam, W

Reliable statistical inference requires accurate population variance estimate, especially in domains where measurement limitations and intrinsic variability impact data. Applying traditional estima...

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Characterizing ECOPD Phenotypes: Associations with In-Hospital Outcomes and Immunoinflammatory Mechanisms.

Wang, Q Wang, L Zhang, L Zhao, C Liu, Y Liu, L Yuan, L Feng, M Wang, G Li, L Zhang, S Yuan, Y Kang, D Zhang, X

BACKGROUND: Hospitalization due to exacerbations of chronic obstructive pulmonary disease (ECOPD) is linked to substantial mortality rates. OBJECTIVE: This study aimed to identify the clinical and ...

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AORI-HAP: a multidimensional risk index to predict in-hospital adverse outcomes in asthma exacerbations.

Yuan, L Zhao, C Wang, L Zhang, L Liu, Y Liu, L Feng, M Melén, E Wang, G Zhang, S Yuan, Y Wang, Q Li, Y Kang, D Zhang, X

BACKGROUND: Despite therapeutic advancements, asthma exacerbations (AEs) remain a major clinical challenge, with immune-inflammatory patterns incompletely characterized. Current guidelines lack rob...

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Indigenous peoples’ voices and engagement on climate change: towards improved health and wellbeing

Lansbury, N Mosby, V Creamer, SJ Moggridge, B Evans, GR Pecl, G Ireland, L

Western climate science largely fails to value, engage with and apply Indigenous Knowledges in a meaningful way. Here, we explore the ways in which the current gap in Indigenous Knowledges and repr...

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