Reliable structural interpretation of small-angle scattering data from bio-molecules in solution - The importance of quality control and a standard reporting framework

Jacques, DA; Guss, JM; Trewhella, J

Reliable structural interpretation of small-angle scattering data from bio-molecules in solution - The importance of quality control and a standard reporting framework

Jacques, DA

Guss, JM Trewhella, J

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Publication Type:: Journal Article
Citation:: BMC Structural Biology, 2012, 12
Issue Date:: 2012-05-18

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Field	Value	Language
dc.contributor.author	Jacques, DA https://orcid.org/0000-0002-6426-4510	en_US
dc.contributor.author	Guss, JM	en_US
dc.contributor.author	Trewhella, J	en_US
dc.date.available	2012-05-17	en_US
dc.date.issued	2012-05-18	en_US
dc.identifier.citation	BMC Structural Biology, 2012, 12	en_US
dc.identifier.uri	http://hdl.handle.net/10453/115288
dc.description.abstract	Small-angle scattering is becoming an increasingly popular tool for the study of bio-molecular structures in solution. The large number of publications with 3D-structural models generated from small-angle solution scattering data has led to a growing consensus for the need to establish a standard reporting framework for their publication. The International Union of Crystallography recently established a set of guidelines for the necessary information required for the publication of such structural models. Here we describe the rationale for these guidelines and the importance of standardising the way in which small-angle scattering data from bio-molecules and associated structural interpretations are reported. © 2012 Jacques et al.; licensee BioMed Central Ltd.	en_US
dc.relation.ispartof	BMC Structural Biology	en_US
dc.relation.isbasedon	10.1186/1472-6807-12-9	en_US
dc.subject.classification	Biophysics	en_US
dc.subject.mesh	Proteins	en_US
dc.subject.mesh	Solutions	en_US
dc.subject.mesh	Reproducibility of Results	en_US
dc.subject.mesh	Research Design	en_US
dc.subject.mesh	Reference Standards	en_US
dc.subject.mesh	Quality Control	en_US
dc.subject.mesh	Scattering, Small Angle	en_US
dc.title	Reliable structural interpretation of small-angle scattering data from bio-molecules in solution - The importance of quality control and a standard reporting framework	en_US
dc.type	Journal Article
utslib.citation.volume	12	en_US
utslib.for	1199 Other Medical and Health Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
utslib.copyright.status	open_access
pubs.publication-status	Published	en_US
pubs.volume	12	en_US

Abstract:

Small-angle scattering is becoming an increasingly popular tool for the study of bio-molecular structures in solution. The large number of publications with 3D-structural models generated from small-angle solution scattering data has led to a growing consensus for the need to establish a standard reporting framework for their publication. The International Union of Crystallography recently established a set of guidelines for the necessary information required for the publication of such structural models. Here we describe the rationale for these guidelines and the importance of standardising the way in which small-angle scattering data from bio-molecules and associated structural interpretations are reported. © 2012 Jacques et al.; licensee BioMed Central Ltd.

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http://hdl.handle.net/10453/115288