The Characterization of Laser Ablation Patterns and a New Definition of Resolution in Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-IMS)

O’Rourke, MB; Raymond, BBA; Padula, MP

The Characterization of Laser Ablation Patterns and a New Definition of Resolution in Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-IMS)

O’Rourke, MB Raymond, BBA

Padula, MP

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Publication Type:: Journal Article
Citation:: Journal of the American Society for Mass Spectrometry, 2017, 28 (5), pp. 895 - 900
Issue Date:: 2017-05-01

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Field	Value	Language
dc.contributor.author	O’Rourke, MB	en_US
dc.contributor.author	Raymond, BBA https://orcid.org/0000-0003-3610-9289	en_US
dc.contributor.author	Padula, MP https://orcid.org/0000-0002-8283-0643	en_US
dc.date.available	2017-02-13	en_US
dc.date.issued	2017-05-01	en_US
dc.identifier.citation	Journal of the American Society for Mass Spectrometry, 2017, 28 (5), pp. 895 - 900	en_US
dc.identifier.issn	1044-0305	en_US
dc.identifier.uri	http://hdl.handle.net/10453/115396
dc.description.abstract	© 2017, American Society for Mass Spectrometry. Matrix assisted laser desorption ionization imaging mass spectrometry (MALDI-IMS) is a technique that has seen a sharp rise in both use and development. Despite this rapid adoption, there have been few thorough investigations into the actual physical mechanisms that underlie the acquisition of IMS images. We therefore set out to characterize the effect of IMS laser ablation patterns on the surface of a sample. We also concluded that the governing factors that control spatial resolution have not been correctly defined and therefore propose a new definition of resolution. [Figure not available: see fulltext.]	en_US
dc.relation.ispartof	Journal of the American Society for Mass Spectrometry	en_US
dc.relation.isbasedon	10.1007/s13361-017-1632-0	en_US
dc.subject.classification	Analytical Chemistry	en_US
dc.title	The Characterization of Laser Ablation Patterns and a New Definition of Resolution in Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-IMS)	en_US
dc.type	Journal Article
utslib.citation.volume	5	en_US
utslib.citation.volume	28	en_US
utslib.for	0301 Analytical Chemistry	en_US
utslib.for	0306 Physical Chemistry (incl. Structural)	en_US
utslib.for	0304 Medicinal and Biomolecular Chemistry	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - ithree - Institute of Infection, Immunity and Innovation
utslib.copyright.status	closed_access
pubs.issue	5	en_US
pubs.publication-status	Published	en_US
pubs.volume	28	en_US

Abstract:

© 2017, American Society for Mass Spectrometry. Matrix assisted laser desorption ionization imaging mass spectrometry (MALDI-IMS) is a technique that has seen a sharp rise in both use and development. Despite this rapid adoption, there have been few thorough investigations into the actual physical mechanisms that underlie the acquisition of IMS images. We therefore set out to characterize the effect of IMS laser ablation patterns on the surface of a sample. We also concluded that the governing factors that control spatial resolution have not been correctly defined and therefore propose a new definition of resolution. [Figure not available: see fulltext.]

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/115396