Aluminum triflate catalyzed tandem reactions of d -galactal: Toward chiral benzopyrans, chromenes, and chromans

Publication Type:
Journal Article
Organic Letters, 2014, 16 (17), pp. 4543 - 4545
Issue Date:
Full metadata record
Files in This Item:
Filename Description Size
4BDE21FA-0411-41CC-BDD9-B21B31068439 am.pdfAccepted Manuscript Version438.33 kB
Adobe PDF
© 2014 American Chemical Society. 3,4,6-Tri-O-acetyl-d-galactal is selectively converted into 1-O-aryl-2-deoxy derivatives or chiral bridged benzopyrans under Al(OTf)3 catalysis, depending on reaction conditions. The benzopyrans react with Al(OTf)3/acetic anhydride in ring-opening reactions in the absence or presence of acetic acid to selectively produce chiral chromenes or chromans, respectively, in high yields.
Please use this identifier to cite or link to this item: