Implications of mutation of organelle genomes for organelle function and evolution

Raven, JA

Implications of mutation of organelle genomes for organelle function and evolution

Raven, JA

Permalink

Publication Type:: Journal Article
Citation:: Journal of Experimental Botany, 2015, 66 (19), pp. 5639 - 5650
Issue Date:: 2015-01-01

Closed Access

	Filename	Description	Size
	\\utsfs.adsroot.uts.edu.au\homes\staff\108848\Desktop\erv298.pdf	Published Version	651.12 kB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Raven, JA https://orcid.org/0000-0002-2789-3297	en_US
dc.date.issued	2015-01-01	en_US
dc.identifier.citation	Journal of Experimental Botany, 2015, 66 (19), pp. 5639 - 5650	en_US
dc.identifier.issn	0022-0957	en_US
dc.identifier.uri	http://hdl.handle.net/10453/118585
dc.description.abstract	© 2015 The Author. Organelle genomes undergo more variation, including that resulting from damage, than eukaryotic nuclear genomes, or bacterial genomes, under the same conditions. Recent advances in characterizing the changes to genomes of chloroplasts and mitochondria of Zea mays should, when applied more widely, help our understanding of how damage to organelle genomes relates to how organelle function is maintained through the life of individuals and in succeeding generations. Understanding of the degree of variation in the changes to organelle DNA and its repair among photosynthetic organisms might help to explain the variations in the rate of nucleotide substitution among organelle genomes. Further studies of organelle DNA variation, including that due to damage and its repair might also help us to understand why the extent of DNA turnover in the organelles is so much greater than that in their bacterial (cyanobacteria for chloroplasts, proteobacteria for mitochondria) relatives with similar rates of production of DNA-damaging reactive oxygen species. Finally, from the available data, even the longest-lived organelle-encoded proteins, and the RNAs needed for their synthesis, are unlikely to maintain organelle function for much more than a week after the complete loss of organelle DNA.	en_US
dc.relation.ispartof	Journal of Experimental Botany	en_US
dc.relation.isbasedon	10.1093/jxb/erv298	en_US
dc.subject.classification	Plant Biology & Botany	en_US
dc.subject.mesh	Organelles	en_US
dc.subject.mesh	Plants	en_US
dc.subject.mesh	Zea mays	en_US
dc.subject.mesh	Mutation	en_US
dc.subject.mesh	Biological Evolution	en_US
dc.title	Implications of mutation of organelle genomes for organelle function and evolution	en_US
dc.type	Journal Article
utslib.citation.volume	19	en_US
utslib.citation.volume	66	en_US
utslib.for	0607 Plant Biology	en_US
utslib.for	0703 Crop and Pasture Production	en_US
utslib.for	0604 Genetics	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
utslib.copyright.status	closed_access
pubs.issue	19	en_US
pubs.publication-status	Published	en_US
pubs.volume	66	en_US

Abstract:

© 2015 The Author. Organelle genomes undergo more variation, including that resulting from damage, than eukaryotic nuclear genomes, or bacterial genomes, under the same conditions. Recent advances in characterizing the changes to genomes of chloroplasts and mitochondria of Zea mays should, when applied more widely, help our understanding of how damage to organelle genomes relates to how organelle function is maintained through the life of individuals and in succeeding generations. Understanding of the degree of variation in the changes to organelle DNA and its repair among photosynthetic organisms might help to explain the variations in the rate of nucleotide substitution among organelle genomes. Further studies of organelle DNA variation, including that due to damage and its repair might also help us to understand why the extent of DNA turnover in the organelles is so much greater than that in their bacterial (cyanobacteria for chloroplasts, proteobacteria for mitochondria) relatives with similar rates of production of DNA-damaging reactive oxygen species. Finally, from the available data, even the longest-lived organelle-encoded proteins, and the RNAs needed for their synthesis, are unlikely to maintain organelle function for much more than a week after the complete loss of organelle DNA.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/118585