HPLC-VALIDATION OF MOXIFLOXACIN

Publisher:
International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL)
Publication Type:
Journal Article
Citation:
International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL), 2016, 5 (3), pp. 2092 - 2098 (6)
Issue Date:
2016-05-01
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The structure formula of moxifloxacin is described as follows: 8 methoxy flouroquinolone: and it is broad spectrum antibiotic [1, 2].we study moxifloxacin by IV drug delivery system. And for its study following apparatus is used; 1-a reversed-phase Lichrospher RP-18 column, 2-a mobile phase which is composed of different solvents. It is detected at a wavelength of 290 nm. By this method the retention time of moxifloxacin is very short. When we detect it in plasma and brain tissue linear curves are obtained. .The advantage of this method is that we can detect the bacteria in plasma and brain tissues by this method.
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