A promising dual mode SPECT/CT imaging platform based on <sup>99m</sup>Tc-labeled multifunctional dendrimer-entrapped gold nanoparticles

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Journal Article
Journal of Materials Chemistry B, 2017, 5 (21), pp. 3810 - 3815
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© 2017 The Royal Society of Chemistry. Multifunctional 99mTc-labeled dendrimer-entrapped gold nanoparticles (99mTc-Au DENPs) were designed and synthesized. Our results show that the type of surface groups (acetyl or hydroxyl) significantly impact the biodistribution profile of the 99mTc-Au DENPs, thereby allowing for preferential SPECT/CT imaging of different organs.
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