Emerging pathogenic links between microbiota and the gut-lung axis

Budden, KF; Gellatly, SL; Wood, DLA; Cooper, MA; Morrison, M; Hugenholtz, P; Hansbro, PM

Emerging pathogenic links between microbiota and the gut-lung axis

Budden, KF Gellatly, SL Wood, DLA Cooper, MA Morrison, M Hugenholtz, P Hansbro, PM

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Publication Type:: Journal Article
Citation:: Nature Reviews Microbiology, 2017, 15 (1), pp. 55 - 63
Issue Date:: 2017-01-01

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Field	Value	Language
dc.contributor.author	Budden, KF	en_US
dc.contributor.author	Gellatly, SL	en_US
dc.contributor.author	Wood, DLA	en_US
dc.contributor.author	Cooper, MA	en_US
dc.contributor.author	Morrison, M	en_US
dc.contributor.author	Hugenholtz, P	en_US
dc.contributor.author	Hansbro, PM https://orcid.org/0000-0002-4741-3035	en_US
dc.date.issued	2017-01-01	en_US
dc.identifier.citation	Nature Reviews Microbiology, 2017, 15 (1), pp. 55 - 63	en_US
dc.identifier.issn	1740-1526	en_US
dc.identifier.uri	http://hdl.handle.net/10453/126230
dc.description.abstract	© 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. The microbiota is vital for the development of the immune system and homeostasis. Changes in microbial composition and function, termed dysbiosis, in the respiratory tract and the gut have recently been linked to alterations in immune responses and to disease development in the lungs. In this Opinion article, we review the microbial species that are usually found in healthy gastrointestinal and respiratory tracts, their dysbiosis in disease and interactions with the gut-lung axis. Although the gut-lung axis is only beginning to be understood, emerging evidence indicates that there is potential for manipulation of the gut microbiota in the treatment of lung diseases.	en_US
dc.relation.ispartof	Nature Reviews Microbiology	en_US
dc.relation.isbasedon	10.1038/nrmicro.2016.142	en_US
dc.subject.classification	Microbiology	en_US
dc.subject.mesh	Gastrointestinal Tract	en_US
dc.subject.mesh	Lung	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Bacteria	en_US
dc.subject.mesh	Respiratory Tract Infections	en_US
dc.subject.mesh	Lung Diseases	en_US
dc.subject.mesh	Dysbiosis	en_US
dc.subject.mesh	Gastrointestinal Microbiome	en_US
dc.title	Emerging pathogenic links between microbiota and the gut-lung axis	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	15	en_US
utslib.for	0605 Microbiology	en_US
utslib.for	1108 Medical Microbiology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	open_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	15	en_US

Abstract:

© 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. The microbiota is vital for the development of the immune system and homeostasis. Changes in microbial composition and function, termed dysbiosis, in the respiratory tract and the gut have recently been linked to alterations in immune responses and to disease development in the lungs. In this Opinion article, we review the microbial species that are usually found in healthy gastrointestinal and respiratory tracts, their dysbiosis in disease and interactions with the gut-lung axis. Although the gut-lung axis is only beginning to be understood, emerging evidence indicates that there is potential for manipulation of the gut microbiota in the treatment of lung diseases.

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http://hdl.handle.net/10453/126230