Versatile multicolor nanodiamond probes for intracellular imaging and targeted labeling

Bray, K; Cheung, L; Hossain, KR; Aharonovich, I; Valenzuela, SM; Shimoni, O

Versatile multicolor nanodiamond probes for intracellular imaging and targeted labeling

Bray, K Cheung, L Hossain, KR

Aharonovich, I

Valenzuela, SM

Shimoni, O

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Publication Type:: Journal Article
Citation:: Journal of Materials Chemistry B, 2018, 6 (19), pp. 3078 - 3084
Issue Date:: 2018-01-01

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Field	Value	Language
dc.contributor.author	Bray, K	en_US
dc.contributor.author	Cheung, L	en_US
dc.contributor.author	Hossain, KR https://orcid.org/0000-0003-4506-1491	en_US
dc.contributor.author	Aharonovich, I https://orcid.org/0000-0003-4304-3935	en_US
dc.contributor.author	Valenzuela, SM https://orcid.org/0000-0001-5934-6047	en_US
dc.contributor.author	Shimoni, O https://orcid.org/0000-0001-8822-1024	en_US
dc.date.available	2020-05-25T19:07:01Z
dc.date.issued	2018-01-01	en_US
dc.identifier.citation	Journal of Materials Chemistry B, 2018, 6 (19), pp. 3078 - 3084	en_US
dc.identifier.issn	2050-7518	en_US
dc.identifier.uri	http://hdl.handle.net/10453/129120
dc.description.abstract	© 2018 The Royal Society of Chemistry. We report on the sizable production of fluorescent nanodiamonds (FNDs) containing a near infrared (NIR) color center-namely the silicon vacancy (SiV) defect, and their first demonstration inside cells for bio-imaging. We further demonstrate a concept of multi-color bio-imaging using FNDs to investigate intercellular processes using two types of FNDs. Due to their specific spectral properties, SiV FNDs can be distinguished from common nitrogen-vacancy (NV) FNDs and show a distinct initial spreading throughout the cell interior. The reported results are the first demonstration of multi-color labeling with FNDs that are especially interesting for in vivo bio-imaging due to their stable fluorescence.	en_US
dc.relation	http://purl.org/au-research/grants/arc/IH150100028
dc.relation	http://purl.org/au-research/grants/nhmrc/APP1101258
dc.relation.ispartof	Journal of Materials Chemistry B	en_US
dc.relation.isbasedon	10.1039/c8tb00508g	en_US
dc.title	Versatile multicolor nanodiamond probes for intracellular imaging and targeted labeling	en_US
dc.type	Journal Article
utslib.citation.volume	19	en_US
utslib.citation.volume	6	en_US
utslib.for	0303 Macromolecular and Materials Chemistry	en_US
utslib.for	0903 Biomedical Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
utslib.copyright.status	open_access
pubs.issue	19	en_US
pubs.publication-status	Published	en_US
pubs.volume	6	en_US

Abstract:

© 2018 The Royal Society of Chemistry. We report on the sizable production of fluorescent nanodiamonds (FNDs) containing a near infrared (NIR) color center-namely the silicon vacancy (SiV) defect, and their first demonstration inside cells for bio-imaging. We further demonstrate a concept of multi-color bio-imaging using FNDs to investigate intercellular processes using two types of FNDs. Due to their specific spectral properties, SiV FNDs can be distinguished from common nitrogen-vacancy (NV) FNDs and show a distinct initial spreading throughout the cell interior. The reported results are the first demonstration of multi-color labeling with FNDs that are especially interesting for in vivo bio-imaging due to their stable fluorescence.

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http://hdl.handle.net/10453/129120