Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307

Field	Value	Language
dc.contributor.author	Wyres, K	en_US
dc.contributor.author	Hawkey, J https://orcid.org/0000-0001-9661-5293	en_US
dc.contributor.author	Hetland, MAK https://orcid.org/0000-0003-4247-8304	en_US
dc.contributor.author	Fostervold, A	en_US
dc.contributor.author	Wick, R	en_US
dc.contributor.author	Judd, L https://orcid.org/0000-0003-3613-4839	en_US
dc.contributor.author	Hamidian, M https://orcid.org/0000-0002-3614-7261	en_US
dc.contributor.author	Howden, B https://orcid.org/0000-0003-0237-1473	en_US
dc.contributor.author	Löhr, I	en_US
dc.contributor.author	Holt, K https://orcid.org/0000-0003-3949-2471	en_US
dc.date.issued	2018-06-21	en_US
dc.identifier.citation	2018	en_US
dc.identifier.uri	http://hdl.handle.net/10453/129452
dc.description.abstract	Abstract Recent reports indicate the emergence of a new carbapenemase producing Klebsiella pneumoniae clone, ST307. Here we show that ST307 emerged in the mid-1990s (nearly 20 years prior to its first report), is already globally distributed and is intimately associated with a conserved plasmid harbouring the bla CTX-M-15 extended-spectrum beta-lactamase (ESBL) gene plus other antimicrobial resistance determinants. Our findings support the need for enhanced surveillance of this widespread ESBL clone in which carbapenem resistance is now emerging.	en_US
dc.title	Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - ithree - Institute of Infection, Immunity and Innovation
utslib.copyright.status	open_access
pubs.declined	2019-01-10T16:47:26.288+1100

Abstract:

Abstract Recent reports indicate the emergence of a new carbapenemase producing Klebsiella pneumoniae clone, ST307. Here we show that ST307 emerged in the mid-1990s (nearly 20 years prior to its first report), is already globally distributed and is intimately associated with a conserved plasmid harbouring the bla CTX-M-15 extended-spectrum beta-lactamase (ESBL) gene plus other antimicrobial resistance determinants. Our findings support the need for enhanced surveillance of this widespread ESBL clone in which carbapenem resistance is now emerging.

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http://hdl.handle.net/10453/129452