Recent Trends of Nano-material as Antimicrobial Agents

Aggarwal, T; Wadhwa, R; Thapliyal, N; Gupta, R; Hansbro, PM; Dua, K; Maurya, PK

Recent Trends of Nano-material as Antimicrobial Agents

Aggarwal, T Wadhwa, R Thapliyal, N Gupta, R Hansbro, PM

Dua, K

Maurya, PK

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Publisher:: Springer
Publication Type:: Chapter
Citation:: Nanotechnology in Modern Animal Biotechnology, 2019, 1, 1 pp. 173 - 193
Issue Date:: 2019-02-01

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Field	Value	Language
dc.contributor.author	Aggarwal, T	en_US
dc.contributor.author	Wadhwa, R	en_US
dc.contributor.author	Thapliyal, N	en_US
dc.contributor.author	Gupta, R	en_US
dc.contributor.author	Hansbro, PM https://orcid.org/0000-0002-4741-3035	en_US
dc.contributor.author	Dua, K https://orcid.org/0000-0002-7507-1159	en_US
dc.contributor.author	Maurya, PK	en_US
dc.contributor.editor	Singh, S	en_US
dc.contributor.editor	Maurya, PK	en_US
dc.date.issued	2019-02-01	en_US
dc.identifier.citation	Nanotechnology in Modern Animal Biotechnology, 2019, 1, 1 pp. 173 - 193	en_US
dc.identifier.isbn	9811360049	en_US
dc.identifier.isbn	9789811360046	en_US
dc.identifier.uri	http://hdl.handle.net/10453/132670
dc.description.abstract	Nanomaterial has been employed as an alternative to antibiotics, diagnostic tools and delivery of therapeutics. In particular, nanomaterial has grabbed the attention of researchers due to their antimicrobial properties due to the emergence of multi-drug resistance of several micro-organisms. The present chapter highlights the antimicrobial nanomaterials with their mechanism of action along with their broad spectrum applications such as silver nanomaterial is antimicrobial in nature and is effective in drug delivery. Metallic, non-metallic and natural/ biodegradable nanomaterials have been discussed as potential antimicrobial and their mode of action. The mechanism of antimicrobial nanomaterial is poorly understood, but oxidative stress, non-oxidative action, inhibition of cell adhesion, decline in biofilm formation, obstructed quoram sensing and metal ion release are attributed to be as the major reasons. In addition, the limitation and toxicity with the clinical and environmental applications are also described.	en_US
dc.publisher	Springer	en_US
dc.relation	http://purl.org/au-research/grants/nhmrc/GNT1079187
dc.relation.ispartof	Nanotechnology in Modern Animal Biotechnology	en_US
dc.relation.isbasedon	10.1007/978-981-13-6004-6	en_US
dc.rights	This is a post-peer-review, pre-copyedit version of an article published in Nanotechnology in Modern Animal Biotechnology. The final authenticated version is available online at: https://dx.doi.org/10.1007/978-981-13-6004-6.	en_US
dc.title	Recent Trends of Nano-material as Antimicrobial Agents	en_US
dc.type	Chapter
utslib.citation.volume	1	en_US
utslib.location	Singapore	en_US
utslib.for	111504 Pharmaceutical Sciences	en_US
utslib.for	1108 Medical Microbiology	en_US
utslib.citation.edition	1	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney/Graduate School of Health
utslib.copyright.status	open_access
pubs.consider-herdc	false	en_US
pubs.edition	1	en_US
pubs.place-of-publication	Singapore	en_US
pubs.publication-status	Published	en_US
pubs.volume	1	en_US

Abstract:

Nanomaterial has been employed as an alternative to antibiotics, diagnostic tools and delivery of therapeutics. In particular, nanomaterial has grabbed the attention of researchers due to their antimicrobial properties due to the emergence of multi-drug resistance of several micro-organisms. The present chapter highlights the antimicrobial nanomaterials with their mechanism of action along with their broad spectrum applications such as silver nanomaterial is antimicrobial in nature and is effective in drug delivery. Metallic, non-metallic and natural/ biodegradable nanomaterials have been discussed as potential antimicrobial and their mode of action. The mechanism of antimicrobial nanomaterial is poorly understood, but oxidative stress, non-oxidative action, inhibition of cell adhesion, decline in biofilm formation, obstructed quoram sensing and metal ion release are attributed to be as the major reasons. In addition, the limitation and toxicity with the clinical and environmental applications are also described.

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http://hdl.handle.net/10453/132670