The isolation and nucleotide sequence of the complex AROM locus of Aspergilus nidulans

Oxford Univ Press United Kingdom
Publication Type:
Journal Article
Nucleic Acids Research, 1986, 14 (5), pp. 2201 - 2213
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The AROM locus of A.nidulans, which governs five consecutive steps in pre-chorismate aromatic amino acid biosynthesis, has been cloned in a bacteriophage vector. The nucleotide sequence of the locus reveals a single, open reading-frame of 4,812 base-pairs, apparently without introns. An internal segment of the A.nidulans AROM sequence has extensive homology with the E.coli aroA gene that encodes the 5-enolpyruvylshikimate 3-phosphate synthase.
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