The use of tethered bilayer lipid membranes to identify the mechanisms of antimicrobial peptide interactions with lipid bilayers

Alghalayini, A; Garcia, A; Berry, T; Cranfield, CG

The use of tethered bilayer lipid membranes to identify the mechanisms of antimicrobial peptide interactions with lipid bilayers

Alghalayini, A

Garcia, A

Berry, T

Cranfield, CG

Permalink

Publication Type:: Journal Article
Citation:: Antibiotics, 2019, 8 (1)
Issue Date:: 2019-03-01

Open Access

Copyright Clearance Process

Recently Added
In Progress
Open Access

This item is open access.

Adobe PDF

Download Published VersionAdobe PDF (2.99 MB)

View on publisher's site

View statistics

Full metadata record

Field	Value	Language
dc.contributor.author	Alghalayini, A https://orcid.org/0000-0002-2308-0256	en_US
dc.contributor.author	Garcia, A https://orcid.org/0000-0002-1159-4567	en_US
dc.contributor.author	Berry, T https://orcid.org/0000-0002-2882-0313	en_US
dc.contributor.author	Cranfield, CG https://orcid.org/0000-0003-3608-5440	en_US
dc.date.available	2019-01-29	en_US
dc.date.issued	2019-03-01	en_US
dc.identifier.citation	Antibiotics, 2019, 8 (1)	en_US
dc.identifier.uri	http://hdl.handle.net/10453/133086
dc.description.abstract	© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This review identifies the ways in which tethered bilayer lipid membranes (tBLMs) can be used for the identification of the actions of antimicrobials against lipid bilayers. Much of the new research in this area has originated, or included researchers from, the southern hemisphere, Australia and New Zealand in particular. More and more, tBLMs are replacing liposome release assays, black lipid membranes and patch-clamp electrophysiological techniques because they use fewer reagents, are able to obtain results far more quickly and can provide a uniformity of responses with fewer artefacts. In this work, we describe how tBLM technology can and has been used to identify the actions of numerous antimicrobial agents.	en_US
dc.relation	http://purl.org/au-research/grants/arc/DP160101664
dc.relation	http://purl.org/au-research/grants/arc/IH150100028
dc.relation.ispartof	Antibiotics	en_US
dc.relation.isbasedon	10.3390/antibiotics8010012	en_US
dc.title	The use of tethered bilayer lipid membranes to identify the mechanisms of antimicrobial peptide interactions with lipid bilayers	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	8	en_US
utslib.for	0601 Biochemistry and Cell Biology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Students
utslib.copyright.status	open_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	8	en_US

Abstract:

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This review identifies the ways in which tethered bilayer lipid membranes (tBLMs) can be used for the identification of the actions of antimicrobials against lipid bilayers. Much of the new research in this area has originated, or included researchers from, the southern hemisphere, Australia and New Zealand in particular. More and more, tBLMs are replacing liposome release assays, black lipid membranes and patch-clamp electrophysiological techniques because they use fewer reagents, are able to obtain results far more quickly and can provide a uniformity of responses with fewer artefacts. In this work, we describe how tBLM technology can and has been used to identify the actions of numerous antimicrobial agents.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/133086