Microencapsulated iNOS-expressing cells cause tumor suppression in mice

Federation Amer Soc Exp Biol
Publication Type:
Journal Article
Faseb Journal, 2002, 16 pp. 213 - 215
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Macrophages are capable of killing tumor cells by releasing nitric oxide (NO) and reactive nitrogen species after expression of the inducible nitric oxide synthase (iNOS) gene. We intend to develop a novel cell-based therapy for tumor inhibition using microencapsulated cells capable of expressing iNOS under control of a regulated promoter
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