Nitric Oxide Upregulates Expression Of Dna-Pkcs To Protect Cells From Dna-Damaging Anti-Tumour Agents

Nature Publishing Group
Publication Type:
Journal Article
Nature Cell Biology, 2000, 2 (6), pp. 339 - 345
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Nitric-oxide synthase (NOS) activity has been detected in many human tumours, although its function is unclear. Here we show that exposure of cells to nitric oxide (NO) results in a 4-5-fold increase in expression of the DNA-dependent protein-kinase cata
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