Advances in single particle tracking in living cells

Wang, DJ; Di, XJ; Wang, BM; Wang, F; Guo, ZY; Jin, DY

Advances in single particle tracking in living cells

Wang, DJ Di, XJ Wang, BM

Wang, F

Guo, ZY Jin, DY

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Publication Type:: Journal Article
Citation:: Chinese Optics, 2018, 11 (3), pp. 281 - 295
Issue Date:: 2018-06-01

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Field	Value	Language
dc.contributor.author	Wang, DJ	en_US
dc.contributor.author	Di, XJ	en_US
dc.contributor.author	Wang, BM https://orcid.org/0000-0002-8701-3896	en_US
dc.contributor.author	Wang, F https://orcid.org/0000-0001-7403-3305	en_US
dc.contributor.author	Guo, ZY	en_US
dc.contributor.author	Jin, DY https://orcid.org/0000-0003-1046-2666	en_US
dc.date.issued	2018-06-01	en_US
dc.identifier.citation	Chinese Optics, 2018, 11 (3), pp. 281 - 295	en_US
dc.identifier.issn	2095-1531	en_US
dc.identifier.uri	http://hdl.handle.net/10453/134025
dc.description.abstract	© 2018, China Science Publishing & Media LTD. All right reserved. Single particle tracking(SPT) technique locates and tracks individual fluorescent or scattering particles within a cell with the help of microscope system. Based on the ability of real-time monitoring of the complex and highly dynamic changes in tissue structure within living cells and the ability to provide dynamic relationships between structure and function, SPT has important applications in cell biology. In this review,the mechanism of SPT and its application on cells are summarized. Firstly, the dynamics of SPT are introduced, including single particle localization, trajectory reconstruction and analysis. Then the optical materials and instruments that SPT technology focuses on at the present stage are described. Finally, the application of SPT in cell membrane, intracellular signaling pathway, molecular transport mechanism, genetic information expression, and viral infection mechanism are proposed. In addition, the advance of SPT technology are prospected in this paper.	en_US
dc.relation.ispartof	Chinese Optics	en_US
dc.relation.isbasedon	10.3788/CO.20181103.0281	en_US
dc.title	Advances in single particle tracking in living cells	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.citation.volume	11	en_US
utslib.for	1004 Medical Biotechnology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Electrical and Data Engineering
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
pubs.organisational-group	/University of Technology Sydney/Students
utslib.copyright.status	closed_access
pubs.issue	3	en_US
pubs.publication-status	Published	en_US
pubs.volume	11	en_US

Abstract:

© 2018, China Science Publishing & Media LTD. All right reserved. Single particle tracking(SPT) technique locates and tracks individual fluorescent or scattering particles within a cell with the help of microscope system. Based on the ability of real-time monitoring of the complex and highly dynamic changes in tissue structure within living cells and the ability to provide dynamic relationships between structure and function, SPT has important applications in cell biology. In this review,the mechanism of SPT and its application on cells are summarized. Firstly, the dynamics of SPT are introduced, including single particle localization, trajectory reconstruction and analysis. Then the optical materials and instruments that SPT technology focuses on at the present stage are described. Finally, the application of SPT in cell membrane, intracellular signaling pathway, molecular transport mechanism, genetic information expression, and viral infection mechanism are proposed. In addition, the advance of SPT technology are prospected in this paper.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/134025