Tetraplegia to Overground Stepping Using Non-Invasive Spinal Neuromodulation

Gad, P; Gerasimenko, Y; Edgerton, VR

Tetraplegia to Overground Stepping Using Non-Invasive Spinal Neuromodulation

Gad, P Gerasimenko, Y Edgerton, VR

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Publisher:: IEEE
Publication Type:: Conference Proceeding
Citation:: International IEEE/EMBS Conference on Neural Engineering, NER, 2019, 2019-March, pp. 89-92
Issue Date:: 2019-05-16

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Field	Value	Language
dc.contributor.author	Gad, P
dc.contributor.author	Gerasimenko, Y
dc.contributor.author	Edgerton, VR
dc.date	2019-03-20
dc.date.accessioned	2020-06-12T06:24:29Z
dc.date.available	2020-06-12T06:24:29Z
dc.date.issued	2019-05-16
dc.identifier.citation	International IEEE/EMBS Conference on Neural Engineering, NER, 2019, 2019-March, pp. 89-92
dc.identifier.isbn	9781538679210
dc.identifier.issn	1948-3546
dc.identifier.issn	1948-3554
dc.identifier.uri	http://hdl.handle.net/10453/141382
dc.description.abstract	© 2019 IEEE. Paralysis of the upper extremity (UE) and lower extremity (LE) following cervical spinal cord injury (SCI) significantly impairs the individual's ability to live independently. While improvement in hand function is considered one of the most desired functions in tetraplegics, few therapies have been successfully developed. Spinal cord stimulation have been shown to be effective in enabling UE and LE function individually. However, improvement of both UE and LE function concomitantly, using the same therapeutic modality has not been demonstrated. This study demonstrates that noninvasive neuromodulation of the spinal cord can improve hand function and stepping abilities in an individual with severe chronic paralysis. The improvements in UE and LE function were accompanied by improvement in autonomic function and sensation below the level of the lesion. Regaining these functions in the individual with severe, chronic paralysis had dramatic impacts functionally and psychologically.
dc.language	en
dc.publisher	IEEE
dc.relation.ispartof	International IEEE/EMBS Conference on Neural Engineering, NER
dc.relation.ispartof	International IEEE/EMBS Conference on Neural Engineering
dc.relation.isbasedon	10.1109/NER.2019.8717096
dc.rights	© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.	en_US
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.title	Tetraplegia to Overground Stepping Using Non-Invasive Spinal Neuromodulation
dc.type	Conference Proceeding
utslib.citation.volume	2019-March
utslib.location.activity	San Francisco, CA, USA
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2020-06-12T06:24:21Z
pubs.finish-date	2019-03-23
pubs.place-of-publication	Piscataway, USA
pubs.publication-status	Published
pubs.start-date	2019-03-20
pubs.volume	2019-March
dc.location	Piscataway, USA

Abstract:

© 2019 IEEE. Paralysis of the upper extremity (UE) and lower extremity (LE) following cervical spinal cord injury (SCI) significantly impairs the individual's ability to live independently. While improvement in hand function is considered one of the most desired functions in tetraplegics, few therapies have been successfully developed. Spinal cord stimulation have been shown to be effective in enabling UE and LE function individually. However, improvement of both UE and LE function concomitantly, using the same therapeutic modality has not been demonstrated. This study demonstrates that noninvasive neuromodulation of the spinal cord can improve hand function and stepping abilities in an individual with severe chronic paralysis. The improvements in UE and LE function were accompanied by improvement in autonomic function and sensation below the level of the lesion. Regaining these functions in the individual with severe, chronic paralysis had dramatic impacts functionally and psychologically.

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http://hdl.handle.net/10453/141382