Harmonizing analytical chemistry and clinical epidemiology for human biomonitoring studies. A case-study of plastic product chemicals in urine.

Heffernan, AL; Gomez-Ramos, MJ; Symeonides, C; Hare, DJ; Vijayasarathy, S; Thompson, K; Mueller, JF; Ponsonby, AL; Sly, PD; BIS Investigator Group

Harmonizing analytical chemistry and clinical epidemiology for human biomonitoring studies. A case-study of plastic product chemicals in urine.

Heffernan, AL Gomez-Ramos, MJ Symeonides, C Hare, DJ Vijayasarathy, S Thompson, K Mueller, JF Ponsonby, AL Sly, PD BIS Investigator Group

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Publisher:: PERGAMON-ELSEVIER SCIENCE LTD
Publication Type:: Journal Article
Citation:: Chemosphere, 2020, 238
Issue Date:: 2020-01

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Field	Value	Language
dc.contributor.author	Heffernan, AL
dc.contributor.author	Gomez-Ramos, MJ
dc.contributor.author	Symeonides, C
dc.contributor.author	Hare, DJ
dc.contributor.author	Vijayasarathy, S
dc.contributor.author	Thompson, K
dc.contributor.author	Mueller, JF
dc.contributor.author	Ponsonby, AL
dc.contributor.author	Sly, PD
dc.contributor.author	BIS Investigator Group
dc.date.accessioned	2020-12-15T00:19:42Z
dc.date.available	2019-08-20
dc.date.available	2020-12-15T00:19:42Z
dc.date.issued	2020-01
dc.identifier.citation	Chemosphere, 2020, 238
dc.identifier.issn	0045-6535
dc.identifier.issn	1879-1298
dc.identifier.uri	http://hdl.handle.net/10453/144689
dc.description.abstract	There is an interdisciplinary interface between analytical chemistry and epidemiology studies with respect to the design, execution, and analysis of environmental epidemiology cohorts and studies. Extracting meaningful results linking chemical exposure to human health outcomes begins at study design and spans the entire workflow. Here we discuss analytical experimental design from an exposure science perspective, and propose a reporting checklist for the design of human biomonitoring studies. We explain key analytical chemistry concepts of blanks and limits of reporting and present a case series of plastic product chemical exposure in prenatal urine specimens from the Barwon Infant Study.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	PERGAMON-ELSEVIER SCIENCE LTD
dc.relation.ispartof	Chemosphere
dc.relation.isbasedon	10.1016/j.chemosphere.2019.124631
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject.classification	Environmental Sciences
dc.subject.classification	Meteorology & Atmospheric Sciences
dc.subject.mesh	Humans
dc.subject.mesh	Phthalic Acids
dc.subject.mesh	Benzhydryl Compounds
dc.subject.mesh	Phenols
dc.subject.mesh	Plastics
dc.subject.mesh	Environmental Pollutants
dc.subject.mesh	Epidemiologic Studies
dc.subject.mesh	Environmental Exposure
dc.subject.mesh	Environmental Monitoring
dc.subject.mesh	Pregnancy
dc.subject.mesh	Research Design
dc.subject.mesh	Female
dc.subject.mesh	Biological Monitoring
dc.subject.mesh	Humans
dc.subject.mesh	Phthalic Acids
dc.subject.mesh	Benzhydryl Compounds
dc.subject.mesh	Phenols
dc.subject.mesh	Plastics
dc.subject.mesh	Environmental Pollutants
dc.subject.mesh	Epidemiologic Studies
dc.subject.mesh	Environmental Exposure
dc.subject.mesh	Environmental Monitoring
dc.subject.mesh	Pregnancy
dc.subject.mesh	Research Design
dc.subject.mesh	Female
dc.subject.mesh	Biological Monitoring
dc.subject.mesh	Benzhydryl Compounds
dc.subject.mesh	Biological Monitoring
dc.subject.mesh	Environmental Exposure
dc.subject.mesh	Environmental Monitoring
dc.subject.mesh	Environmental Pollutants
dc.subject.mesh	Epidemiologic Studies
dc.subject.mesh	Female
dc.subject.mesh	Humans
dc.subject.mesh	Phenols
dc.subject.mesh	Phthalic Acids
dc.subject.mesh	Plastics
dc.subject.mesh	Pregnancy
dc.subject.mesh	Research Design
dc.title	Harmonizing analytical chemistry and clinical epidemiology for human biomonitoring studies. A case-study of plastic product chemicals in urine.
dc.type	Journal Article
utslib.citation.volume	238
utslib.location.activity	England
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2020-12-15T00:19:38Z
pubs.publication-status	Published
pubs.volume	238

Abstract:

There is an interdisciplinary interface between analytical chemistry and epidemiology studies with respect to the design, execution, and analysis of environmental epidemiology cohorts and studies. Extracting meaningful results linking chemical exposure to human health outcomes begins at study design and spans the entire workflow. Here we discuss analytical experimental design from an exposure science perspective, and propose a reporting checklist for the design of human biomonitoring studies. We explain key analytical chemistry concepts of blanks and limits of reporting and present a case series of plastic product chemical exposure in prenatal urine specimens from the Barwon Infant Study.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/144689