Is there an association between the level of ambient air pollution and COVID-19?

Wang, B; Chen, H; Chan, YL; Oliver, BG

Is there an association between the level of ambient air pollution and COVID-19?

Wang, B

Chen, H

Chan, YL Oliver, BG

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Publisher:: AMER PHYSIOLOGICAL SOC
Publication Type:: Journal Article
Citation:: American journal of physiology. Lung cellular and molecular physiology, 2020, 319, (3), pp. L416-L421
Issue Date:: 2020-09

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Field	Value	Language
dc.contributor.author	Wang, B https://orcid.org/0000-0002-8701-3896
dc.contributor.author	Chen, H https://orcid.org/0000-0001-6883-3752
dc.contributor.author	Chan, YL
dc.contributor.author	Oliver, BG
dc.date.accessioned	2020-12-17T01:11:23Z
dc.date.available	2020-12-17T01:11:23Z
dc.date.issued	2020-09
dc.identifier.citation	American journal of physiology. Lung cellular and molecular physiology, 2020, 319, (3), pp. L416-L421
dc.identifier.issn	1522-1504
dc.identifier.issn	1522-1504
dc.identifier.uri	http://hdl.handle.net/10453/144789
dc.description.abstract	Epidemiological studies suggest that environmental factors (e.g., air pollution) can influence the spread and infectivity of coronavirus disease 2019 (COVID-19); however, very few papers have investigated or discussed the mechanism behind the phenomenon. Given the fact that pollution will increase as social distancing rules are relaxed, we summarized the current understanding of how air pollution may affect COVID-19 transmission and discussed several possible mechanisms. Air pollution exposure can dysregulate the human immune response and make people more susceptible to infections, and affect infectivity. For example, in response to exposure to air pollution, angiotensin-converting enzyme 2 will increase, which is the receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This may increase the efficiency of viral infection. It is also possible that air pollution can facilitate SARS-CoV-2 spread by increasing the transmission, and potentially, SARS-CoV-2 can also survive longer when attached to a pollutant.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	AMER PHYSIOLOGICAL SOC
dc.relation	http://purl.org/au-research/grants/nhmrc/APP1158186
dc.relation	Maridulu Budyari Gumal - The Sydney Partnership for Health, Education, Research and Enterprise (SPHERE)N/A
dc.relation	http://purl.org/au-research/grants/nhmrc/APP1079184
dc.relation	http://purl.org/au-research/grants/nhmrc/GNT1158186
dc.relation	http://purl.org/au-research/grants/nhmrc/GNT1079184
dc.relation	http://purl.org/au-research/grants/nhmrc/1158186
dc.relation.ispartof	American journal of physiology. Lung cellular and molecular physiology
dc.relation.isbasedon	10.1152/ajplung.00244.2020
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0606 Physiology, 1116 Medical Physiology
dc.subject.classification	Respiratory System
dc.subject.mesh	Humans
dc.subject.mesh	Coronavirus
dc.subject.mesh	Pneumonia, Viral
dc.subject.mesh	Coronavirus Infections
dc.subject.mesh	Peptidyl-Dipeptidase A
dc.subject.mesh	Air Pollution
dc.subject.mesh	Disease Transmission, Infectious
dc.subject.mesh	Pandemics
dc.subject.mesh	Betacoronavirus
dc.subject.mesh	Humans
dc.subject.mesh	Coronavirus
dc.subject.mesh	Pneumonia, Viral
dc.subject.mesh	Coronavirus Infections
dc.subject.mesh	Peptidyl-Dipeptidase A
dc.subject.mesh	Air Pollution
dc.subject.mesh	Disease Transmission, Infectious
dc.subject.mesh	Pandemics
dc.subject.mesh	Betacoronavirus
dc.subject.mesh	Air Pollution
dc.subject.mesh	Angiotensin-Converting Enzyme 2
dc.subject.mesh	Betacoronavirus
dc.subject.mesh	COVID-19
dc.subject.mesh	Coronavirus
dc.subject.mesh	Coronavirus Infections
dc.subject.mesh	Disease Transmission, Infectious
dc.subject.mesh	Humans
dc.subject.mesh	Pandemics
dc.subject.mesh	Peptidyl-Dipeptidase A
dc.subject.mesh	Pneumonia, Viral
dc.subject.mesh	SARS-CoV-2
dc.title	Is there an association between the level of ambient air pollution and COVID-19?
dc.type	Journal Article
utslib.citation.volume	319
utslib.location.activity	United States
utslib.for	0606 Physiology
utslib.for	1116 Medical Physiology
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2020-12-17T01:11:19Z
pubs.issue	3
pubs.publication-status	Published
pubs.volume	319
utslib.citation.issue	3

Abstract:

Epidemiological studies suggest that environmental factors (e.g., air pollution) can influence the spread and infectivity of coronavirus disease 2019 (COVID-19); however, very few papers have investigated or discussed the mechanism behind the phenomenon. Given the fact that pollution will increase as social distancing rules are relaxed, we summarized the current understanding of how air pollution may affect COVID-19 transmission and discussed several possible mechanisms. Air pollution exposure can dysregulate the human immune response and make people more susceptible to infections, and affect infectivity. For example, in response to exposure to air pollution, angiotensin-converting enzyme 2 will increase, which is the receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This may increase the efficiency of viral infection. It is also possible that air pollution can facilitate SARS-CoV-2 spread by increasing the transmission, and potentially, SARS-CoV-2 can also survive longer when attached to a pollutant.

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http://hdl.handle.net/10453/144789