Goal-directed actions transiently depend on dorsal hippocampus.

Bradfield, LA; Leung, BK; Boldt, S; Liang, S; Balleine, BW

Goal-directed actions transiently depend on dorsal hippocampus.

Bradfield, LA Leung, BK Boldt, S Liang, S Balleine, BW

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Publisher:: NATURE PUBLISHING GROUP
Publication Type:: Journal Article
Citation:: Nature neuroscience, 2020, 23, (10), pp. 1194-1197
Issue Date:: 2020-10

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Field	Value	Language
dc.contributor.author	Bradfield, LA
dc.contributor.author	Leung, BK
dc.contributor.author	Boldt, S
dc.contributor.author	Liang, S
dc.contributor.author	Balleine, BW
dc.date.accessioned	2021-02-11T04:56:51Z
dc.date.available	2020-07-13
dc.date.available	2021-02-11T04:56:51Z
dc.date.issued	2020-10
dc.identifier.citation	Nature neuroscience, 2020, 23, (10), pp. 1194-1197
dc.identifier.issn	1097-6256
dc.identifier.issn	1546-1726
dc.identifier.uri	http://hdl.handle.net/10453/146029
dc.description.abstract	The role of the hippocampus in goal-directed action is currently unclear; studies investigating this issue have produced contradictory results. Here we reconcile these contradictions by demonstrating that, in rats, goal-directed action relies on the dorsal hippocampus, but only transiently, immediately after initial acquisition. Furthermore, we found that goal-directed action also depends transiently on physical context, suggesting a psychological basis for the hippocampal regulation of goal-directed action control.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	NATURE PUBLISHING GROUP
dc.relation.ispartof	Nature neuroscience
dc.relation.isbasedon	10.1038/s41593-020-0693-8
dc.rights	info:eu-repo/semantics/embargoedAccess
dc.subject	1109 Neurosciences, 1701 Psychology, 1702 Cognitive Sciences
dc.subject.classification	Neurology & Neurosurgery
dc.subject.mesh	Hippocampus
dc.subject.mesh	Animals
dc.subject.mesh	Rats, Long-Evans
dc.subject.mesh	Behavior, Animal
dc.subject.mesh	Goals
dc.subject.mesh	Conditioning, Operant
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Animals
dc.subject.mesh	Behavior, Animal
dc.subject.mesh	Conditioning, Operant
dc.subject.mesh	Female
dc.subject.mesh	Goals
dc.subject.mesh	Hippocampus
dc.subject.mesh	Male
dc.subject.mesh	Rats, Long-Evans
dc.title	Goal-directed actions transiently depend on dorsal hippocampus.
dc.type	Journal Article
utslib.citation.volume	23
utslib.location.activity	United States
utslib.for	1109 Neurosciences
utslib.for	1701 Psychology
utslib.for	1702 Cognitive Sciences
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	open_access	*
utslib.copyright.embargo	2022-04-30T00:00:00+1000Z
dc.date.updated	2021-02-11T04:56:37Z
pubs.issue	10
pubs.publication-status	Published
pubs.volume	23
utslib.citation.issue	10

Abstract:

The role of the hippocampus in goal-directed action is currently unclear; studies investigating this issue have produced contradictory results. Here we reconcile these contradictions by demonstrating that, in rats, goal-directed action relies on the dorsal hippocampus, but only transiently, immediately after initial acquisition. Furthermore, we found that goal-directed action also depends transiently on physical context, suggesting a psychological basis for the hippocampal regulation of goal-directed action control.

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http://hdl.handle.net/10453/146029