Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines

Macreadie, IG; Avery, TD; Robinson, TV; Macreadie, P; Barraclough, M; Taylor, DK; Tiekink, ERT

Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines

Macreadie, IG Avery, TD Robinson, TV Macreadie, P

Barraclough, M Taylor, DK Tiekink, ERT

Permalink

Publication Type:: Journal Article
Citation:: Tetrahedron, 2008, 64 (7), pp. 1225 - 1232
Issue Date:: 2008-02-11

Closed Access

	Filename	Description	Size
	2010001950OK.pdf		265.85 kB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Macreadie, IG	en_US
dc.contributor.author	Avery, TD	en_US
dc.contributor.author	Robinson, TV	en_US
dc.contributor.author	Macreadie, P https://orcid.org/0000-0001-7362-0882	en_US
dc.contributor.author	Barraclough, M	en_US
dc.contributor.author	Taylor, DK	en_US
dc.contributor.author	Tiekink, ERT	en_US
dc.date.issued	2008-02-11	en_US
dc.identifier.citation	Tetrahedron, 2008, 64 (7), pp. 1225 - 1232	en_US
dc.identifier.issn	0040-4020	en_US
dc.identifier.uri	http://hdl.handle.net/10453/14670
dc.description.abstract	In an ongoing effort to rationally design new antimicrobials, 47 new 1,2-dioxines have been synthesised. Broad antifungal structure-activity relationships governing aromatically substituted epoxy-1,2-dioxines 2 and 3 and their parent 1,2-dioxines 1 were assessed primarily against the pathogenic yeast, Candida albicans, with haemolytic activity of selected examples also reported. © 2007 Elsevier Ltd. All rights reserved.	en_US
dc.relation.ispartof	Tetrahedron	en_US
dc.relation.isbasedon	10.1016/j.tet.2007.11.071	en_US
dc.subject.classification	Organic Chemistry	en_US
dc.title	Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines	en_US
dc.type	Journal Article
utslib.citation.volume	7	en_US
utslib.citation.volume	64	en_US
utslib.for	0304 Medicinal and Biomolecular Chemistry	en_US
utslib.for	0305 Organic Chemistry	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
utslib.copyright.status	closed_access
pubs.issue	7	en_US
pubs.publication-status	Published	en_US
pubs.volume	64	en_US

Abstract:

In an ongoing effort to rationally design new antimicrobials, 47 new 1,2-dioxines have been synthesised. Broad antifungal structure-activity relationships governing aromatically substituted epoxy-1,2-dioxines 2 and 3 and their parent 1,2-dioxines 1 were assessed primarily against the pathogenic yeast, Candida albicans, with haemolytic activity of selected examples also reported. © 2007 Elsevier Ltd. All rights reserved.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/14670