Structure of the RTP?DNA complex and the mechanism of polar replication fork arrest

Nature America inc
Publication Type:
Journal Article
Nature Structural Biology, 2001, 8 (3), pp. 206 - 210
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The coordinated termination of DNA replication is an important step in the life cycle of bacteria with circular chromosomes, but has only been defined at a molecular level in two systems to date. Here we report the structure of an engineered replication terminator protein (RTP) of Bacillus subtilis in complex with a 21 base pair DNA by X-ray crystallography at 2.5 Å resolution.
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