Malaria Risk and Prevention in Asian Migrants to Angola.

Martins, JF; Marques, C; Nieto-Andrade, B; Kelley, J; Patel, D; Nace, D; Herman, C; Barratt, J; Ponce de León, G; Talundzic, E; Rogier, E; Halsey, ES; Plucinski, MM

Malaria Risk and Prevention in Asian Migrants to Angola.

Martins, JF Marques, C Nieto-Andrade, B Kelley, J Patel, D Nace, D Herman, C Barratt, J

Ponce de León, G Talundzic, E Rogier, E Halsey, ES Plucinski, MM

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Publisher:: American Society of Tropical Medicine and Hygiene
Publication Type:: Journal Article
Citation:: The American journal of tropical medicine and hygiene, 2020, 103, (5), pp. 1918-1926
Issue Date:: 2020-11

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Field	Value	Language
dc.contributor.author	Martins, JF
dc.contributor.author	Marques, C
dc.contributor.author	Nieto-Andrade, B
dc.contributor.author	Kelley, J
dc.contributor.author	Patel, D
dc.contributor.author	Nace, D
dc.contributor.author	Herman, C
dc.contributor.author	Barratt, J https://orcid.org/0000-0001-8711-2408
dc.contributor.author	Ponce de León, G
dc.contributor.author	Talundzic, E
dc.contributor.author	Rogier, E
dc.contributor.author	Halsey, ES
dc.contributor.author	Plucinski, MM
dc.date.accessioned	2021-04-26T06:50:41Z
dc.date.available	2021-04-26T06:50:41Z
dc.date.issued	2020-11
dc.identifier.citation	The American journal of tropical medicine and hygiene, 2020, 103, (5), pp. 1918-1926
dc.identifier.issn	0002-9637
dc.identifier.issn	1476-1645
dc.identifier.uri	http://hdl.handle.net/10453/148395
dc.description.abstract	The number of Asian migrants working in sub-Saharan developing countries like Angola has been increasing. Their malaria risk, prevention, and care-seeking practices have not been characterized. A cross-sectional survey was conducted in 733 Chinese and Southeast Asian migrants in Angola. Respondents were interviewed and provided blood samples. Samples were analyzed to detect <i>Plasmodium</i> antigen and characterize host anti-<i>Plasmodium</i> response. Positive samples were genotyped using the <i>pfs47</i> marker. Most respondents (72%; 95% CI: 68-75) reported using bed nets, but less than 1% reported using chemoprophylaxis. Depending on the assay, 1-4% of respondents had evidence of active malaria infection. By contrast, 55% (95% CI: 52-59) were seropositive for <i>Plasmodium</i> antibodies. Most infections were <i>Plasmodium falciparum</i>, but infection and/or exposure to <i>Plasmodium vivax</i> and <i>Plasmodium malariae</i> was also detected. Seroprevalence by time in Angola showed most exposure occurred locally. One respondent had sufficiently high parasitemia for <i>pfs47</i> genotyping, which showed that the infection was likely locally acquired despite recent travel to home country. Asian migrants to Angola are at substantial risk of malaria. Employers should consider enhanced malaria prevention programs, including chemoprophylaxis; embassies should encourage prevention practices. Angolan healthcare workers should be aware of high malaria exposure in Asian migrants.
dc.format	Print
dc.language	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartof	The American journal of tropical medicine and hygiene
dc.relation.isbasedon	10.4269/ajtmh.20-0706
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	11 Medical and Health Sciences
dc.subject.classification	Tropical Medicine
dc.subject.mesh	Adult
dc.subject.mesh	Angola
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Female
dc.subject.mesh	Humans
dc.subject.mesh	Incidence
dc.subject.mesh	Malaria
dc.subject.mesh	Male
dc.subject.mesh	Middle Aged
dc.subject.mesh	Plasmodium
dc.subject.mesh	Population Surveillance
dc.subject.mesh	Prevalence
dc.subject.mesh	Risk Factors
dc.subject.mesh	Seroepidemiologic Studies
dc.subject.mesh	Transients and Migrants
dc.subject.mesh	Humans
dc.subject.mesh	Plasmodium
dc.subject.mesh	Malaria
dc.subject.mesh	Population Surveillance
dc.subject.mesh	Incidence
dc.subject.mesh	Prevalence
dc.subject.mesh	Risk Factors
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Seroepidemiologic Studies
dc.subject.mesh	Adult
dc.subject.mesh	Middle Aged
dc.subject.mesh	Transients and Migrants
dc.subject.mesh	Angola
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Adult
dc.subject.mesh	Angola
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Female
dc.subject.mesh	Humans
dc.subject.mesh	Incidence
dc.subject.mesh	Malaria
dc.subject.mesh	Male
dc.subject.mesh	Middle Aged
dc.subject.mesh	Plasmodium
dc.subject.mesh	Population Surveillance
dc.subject.mesh	Prevalence
dc.subject.mesh	Risk Factors
dc.subject.mesh	Seroepidemiologic Studies
dc.subject.mesh	Transients and Migrants
dc.title	Malaria Risk and Prevention in Asian Migrants to Angola.
dc.type	Journal Article
utslib.citation.volume	103
utslib.location.activity	United States
utslib.for	11 Medical and Health Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2021-04-26T06:50:39Z
pubs.issue	5
pubs.publication-status	Published
pubs.volume	103
utslib.citation.issue	5

Abstract:

The number of Asian migrants working in sub-Saharan developing countries like Angola has been increasing. Their malaria risk, prevention, and care-seeking practices have not been characterized. A cross-sectional survey was conducted in 733 Chinese and Southeast Asian migrants in Angola. Respondents were interviewed and provided blood samples. Samples were analyzed to detect Plasmodium antigen and characterize host anti-Plasmodium response. Positive samples were genotyped using the pfs47 marker. Most respondents (72%; 95% CI: 68-75) reported using bed nets, but less than 1% reported using chemoprophylaxis. Depending on the assay, 1-4% of respondents had evidence of active malaria infection. By contrast, 55% (95% CI: 52-59) were seropositive for Plasmodium antibodies. Most infections were Plasmodium falciparum, but infection and/or exposure to Plasmodium vivax and Plasmodium malariae was also detected. Seroprevalence by time in Angola showed most exposure occurred locally. One respondent had sufficiently high parasitemia for pfs47 genotyping, which showed that the infection was likely locally acquired despite recent travel to home country. Asian migrants to Angola are at substantial risk of malaria. Employers should consider enhanced malaria prevention programs, including chemoprophylaxis; embassies should encourage prevention practices. Angolan healthcare workers should be aware of high malaria exposure in Asian migrants.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/148395