Synthesis of YTi@Ag nanocomposite and investigation of its structural and antifungal properties
- Publisher:
- Springer Science and Business Media LLC
- Publication Type:
- Journal Article
- Citation:
- Journal of the Iranian Chemical Society, 2020, 17, (1), pp. 103-110
- Issue Date:
- 2020-01-01
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Nazeri2020_Article_SynthesisOfYTiAgNanocompositeA.pdf | 2.08 MB |
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The aim of the current study is to describe the synthesis, characterization, and measurement of optical and antifungal properties of Yb TiO @Ag nanocomposites (YTi@Ag) against three standard Candida species including Candida albicans (ATCC 1023), Candida krusei (ATCC 6258), and Candida tropicalis (ATCC 750). YTi@Ag nanocomposites were synthesized through the sol-gel assistant ultrasonic method in an aqueous solution. The antifungal abilities were performed base on macrodilution method as recommended by the Clinical and Laboratory Standards Institute (CLSI, document M27-A3). SEM, XRD, EDX, and FT-IR were applied to characterize structural and morphological characteristics of nanocomposites. In addition, several antifungal tests were performed to investigate the impact of YTi@Ag nanocomposites on the Candida species. Minimum inhibitory concentration (MIC ) measurements of the YTi@Ag NPs against C. albicans (ATCC 1023), C. krusei (ATCC 6258), and C. tropicalis (ATCC 750) after 24 and 48 h were 4 and 32 µg/ml, respectively. MIC results show that as-synthesized YTi@Ag nanocomposites are efficient as an alternative antibacterial/antifungal agent. The band gap of bare Yb TiO and YTi@Ag nanocomposites is 3 and 2.85 eV, respectively. Ag-doped Yb TiO has advantage over naked Yb TiO which enhances separation of electron–hole pairs which improves antifungal activity. 2 5 2 5 2 5 2 5 50 50
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