Hypoxia as a physiological cue and a pathological stress for coral larvae.

Alderdice, R; Pernice, M; Cárdenas, A; Hughes, DJ; Harrison, PL; Boulotte, N; Chartrand, K; Kühl, M; Suggett, DJ; Voolstra, CR

Hypoxia as a physiological cue and a pathological stress for coral larvae.

Alderdice, R Pernice, M

Cárdenas, A Hughes, DJ Harrison, PL Boulotte, N Chartrand, K Kühl, M Suggett, DJ Voolstra, CR

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Publisher:: Wiley
Publication Type:: Journal Article
Citation:: Mol Ecol, 2021
Issue Date:: 2021-10-30

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Field	Value	Language
dc.contributor.author	Alderdice, R
dc.contributor.author	Pernice, M https://orcid.org/0000-0002-3431-2104
dc.contributor.author	Cárdenas, A
dc.contributor.author	Hughes, DJ
dc.contributor.author	Harrison, PL
dc.contributor.author	Boulotte, N
dc.contributor.author	Chartrand, K
dc.contributor.author	Kühl, M
dc.contributor.author	Suggett, DJ
dc.contributor.author	Voolstra, CR
dc.date.accessioned	2021-11-05T02:35:56Z
dc.date.available	2021-11-05T02:35:56Z
dc.date.issued	2021-10-30
dc.identifier.citation	Mol Ecol, 2021
dc.identifier.issn	0962-1083
dc.identifier.issn	1365-294X
dc.identifier.uri	http://hdl.handle.net/10453/151350
dc.description.abstract	Ocean deoxygenation events are intensifying worldwide and can rapidly drive adult corals into a state of metabolic crisis and bleaching-induced mortality, but whether coral larvae are driven into a similar metabolic crisis remains untested. We experimentally exposed apo-symbiotic coral larvae of Acropora selago to deoxygenation stress with subsequent reoxygenation aligned to their night-day light cycle, and followed their gene expression using RNA-Seq. After 12 hours of deoxygenation stress (~2 mg O2 L-1 ), coral planulae demonstrated a low expression of HIF-targeted hypoxia response genes along with a significantly high expression of PHD2 (a promoter of HIFα proteasomal degradation), similar to corresponding adult samples. Despite exhibiting a consistent swimming phenotype compared to control samples, the differential gene expression observed in planulae exposed to deoxygenation-reoxygenation suggests a disruption of pathways involved in developmental regulation, mitochondrial activity, lipid metabolism, and O2 -sensitive epigenetic regulators. Importantly, we found that treated larvae exhibited a disruption in the expression of HIF-targeted and conserved developmental regulators, e.g., Homeobox HOX, corroborating how changes in external oxygen levels can affect animal growth. We discuss how the observed deoxygenation responses may be indicative of a possible acclimation response or alternatively may imply negative latent impacts for coral larval success.
dc.language	eng
dc.publisher	Wiley
dc.relation	http://purl.org/au-research/grants/arc/DP180100074
dc.relation.ispartof	Mol Ecol
dc.relation.isbasedon	10.1111/mec.16259
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	06 Biological Sciences
dc.subject.classification	Evolutionary Biology
dc.title	Hypoxia as a physiological cue and a pathological stress for coral larvae.
dc.type	Journal Article
utslib.location.activity	England
utslib.for	06 Biological Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - C3 - Climate Change Cluster
utslib.copyright.status	open_access	*
dc.date.updated	2021-11-05T02:35:52Z
pubs.publication-status	Published online

Abstract:

Ocean deoxygenation events are intensifying worldwide and can rapidly drive adult corals into a state of metabolic crisis and bleaching-induced mortality, but whether coral larvae are driven into a similar metabolic crisis remains untested. We experimentally exposed apo-symbiotic coral larvae of Acropora selago to deoxygenation stress with subsequent reoxygenation aligned to their night-day light cycle, and followed their gene expression using RNA-Seq. After 12 hours of deoxygenation stress (~2 mg O2 L-1 ), coral planulae demonstrated a low expression of HIF-targeted hypoxia response genes along with a significantly high expression of PHD2 (a promoter of HIFα proteasomal degradation), similar to corresponding adult samples. Despite exhibiting a consistent swimming phenotype compared to control samples, the differential gene expression observed in planulae exposed to deoxygenation-reoxygenation suggests a disruption of pathways involved in developmental regulation, mitochondrial activity, lipid metabolism, and O2 -sensitive epigenetic regulators. Importantly, we found that treated larvae exhibited a disruption in the expression of HIF-targeted and conserved developmental regulators, e.g., Homeobox HOX, corroborating how changes in external oxygen levels can affect animal growth. We discuss how the observed deoxygenation responses may be indicative of a possible acclimation response or alternatively may imply negative latent impacts for coral larval success.

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http://hdl.handle.net/10453/151350