Preparing Ion Channel Switch Membrane-Based Biosensors.
- Publisher:
- Springer US
- Publication Type:
- Chapter
- Citation:
- Methods in Molecular Biology, 2022, 2402, pp. 13-20
- Issue Date:
- 2022
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Monitoring the changes in membrane conductance using electrical impedance spectroscopy is the platform of membrane-based biosensors in order to detect a specific target molecule. These biosensors represent the amalgamation of an electrical conductor such as gold and a chemically tethered bilayer lipid membrane with specific incorporated ion channels such as gramicidin-A that is further functionalized with detector molecules of interest.
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