Assessment of the efficacy of an advanced tertiary sewage treatment plant to remove biologically active chemicals using endocrine and genotoxicity bioassays

Hamilton, LA; Shiraishi, F; Nakajima, D; Boake, M; Lim, RP; Champeau, O; Tremblay, LA

Assessment of the efficacy of an advanced tertiary sewage treatment plant to remove biologically active chemicals using endocrine and genotoxicity bioassays

Hamilton, LA Shiraishi, F Nakajima, D Boake, M Lim, RP Champeau, O Tremblay, LA

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Publisher:: KeAi
Publication Type:: Journal Article
Citation:: Emerging Contaminants, 2021, 7, pp. 124-131
Issue Date:: 2021-01-01

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Field	Value	Language
dc.contributor.author	Hamilton, LA
dc.contributor.author	Shiraishi, F
dc.contributor.author	Nakajima, D
dc.contributor.author	Boake, M
dc.contributor.author	Lim, RP
dc.contributor.author	Champeau, O
dc.contributor.author	Tremblay, LA
dc.date.accessioned	2022-01-14T22:01:05Z
dc.date.available	2022-01-14T22:01:05Z
dc.date.issued	2021-01-01
dc.identifier.citation	Emerging Contaminants, 2021, 7, pp. 124-131
dc.identifier.issn	2405-6650
dc.identifier.issn	2405-6642
dc.identifier.uri	http://hdl.handle.net/10453/153139
dc.description.abstract	There has been much effort to assess the efficacy of sewage treatment plants to remove chemicals with estrogenic activity, but other modes of toxicity have received less attention. This study assessed the efficacy of advanced tertiary technologies to remove estrogen receptor (ER), aryl hydrocarbon receptor (AhR), retinoic receptor (RAR) agonists and genotoxicity using recombinant gene bioassays. Untreated sewage contained ER, AhR and RAR agonists and was genotoxic. Activated sludge treatment removed over 69% of the ER, AhR and RAR aqueous phase activities. Ozonation and biologically activated carbon processes removed genotoxicity and most receptor agonists to below detection limits. Estrogenic activity was associated with the semi-polar fraction of the aqueous phase and non-polar phase of the influent (maximum 30%). AhR and RAR activities were found in both the aqueous and particulate phases of influent. Only RAR activity was frequently found in the polar fraction of aqueous and particulate phases of the process effluent. In the influent, the greatest RAR activity was found in the polar fraction of the aqueous phase (>65%). Genotoxic activity was detected in all influent fractions but rapidly decreased. The results showed that ER, AhR and RAR agonists were greatly reduced by the advanced tertiary treatment processes.
dc.language	en
dc.publisher	KeAi
dc.relation.ispartof	Emerging Contaminants
dc.relation.isbasedon	10.1016/j.emcon.2021.03.003
dc.rights	info:eu-repo/semantics/openAccess
dc.title	Assessment of the efficacy of an advanced tertiary sewage treatment plant to remove biologically active chemicals using endocrine and genotoxicity bioassays
dc.type	Journal Article
utslib.citation.volume	7
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	open_access	*
pubs.consider-herdc	false
dc.date.updated	2022-01-14T22:01:04Z
pubs.publication-status	Published
pubs.volume	7

Abstract:

There has been much effort to assess the efficacy of sewage treatment plants to remove chemicals with estrogenic activity, but other modes of toxicity have received less attention. This study assessed the efficacy of advanced tertiary technologies to remove estrogen receptor (ER), aryl hydrocarbon receptor (AhR), retinoic receptor (RAR) agonists and genotoxicity using recombinant gene bioassays. Untreated sewage contained ER, AhR and RAR agonists and was genotoxic. Activated sludge treatment removed over 69% of the ER, AhR and RAR aqueous phase activities. Ozonation and biologically activated carbon processes removed genotoxicity and most receptor agonists to below detection limits. Estrogenic activity was associated with the semi-polar fraction of the aqueous phase and non-polar phase of the influent (maximum 30%). AhR and RAR activities were found in both the aqueous and particulate phases of influent. Only RAR activity was frequently found in the polar fraction of aqueous and particulate phases of the process effluent. In the influent, the greatest RAR activity was found in the polar fraction of the aqueous phase (>65%). Genotoxic activity was detected in all influent fractions but rapidly decreased. The results showed that ER, AhR and RAR agonists were greatly reduced by the advanced tertiary treatment processes.

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http://hdl.handle.net/10453/153139