Improved the specificity of peroxidase-like carbonized polydopamine nanotubes with high nitrogen doping for glutathione detection

Zhang, T; Li, H; Liu, M; Zhou, H; Zhang, Z; Yu, C; Wang, C; Wang, G

Improved the specificity of peroxidase-like carbonized polydopamine nanotubes with high nitrogen doping for glutathione detection

Zhang, T Li, H Liu, M Zhou, H Zhang, Z Yu, C Wang, C Wang, G

Permalink

Publisher:: ELSEVIER SCIENCE SA
Publication Type:: Journal Article
Citation:: Sensors and Actuators, B: Chemical, 2021, 341
Issue Date:: 2021-08-15

Closed Access

	Filename	Description	Size
	1-s2.0-S0925400521005566-main.pdf	Published version	3.51 MB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Zhang, T
dc.contributor.author	Li, H
dc.contributor.author	Liu, M
dc.contributor.author	Zhou, H
dc.contributor.author	Zhang, Z
dc.contributor.author	Yu, C
dc.contributor.author	Wang, C
dc.contributor.author	Wang, G https://orcid.org/0000-0003-4295-8578
dc.date.accessioned	2022-02-06T22:31:59Z
dc.date.available	2022-02-06T22:31:59Z
dc.date.issued	2021-08-15
dc.identifier.citation	Sensors and Actuators, B: Chemical, 2021, 341
dc.identifier.issn	0925-4005
dc.identifier.issn	0925-4005
dc.identifier.uri	http://hdl.handle.net/10453/154228
dc.description.abstract	The introduction of nitrogen heteroatoms into enzyme-like carbon materials is an effective strategy to enhance both catalytic activity and specificity. Herein, we described the preparation of the carbonized polydopamine nanotubes (C-DPANTs) using sacrificial halloysite nanotubes (HNTs) templates. The resulting nitrogen doped C-PDANTs (N-doped C-PDANTs) exhibit solely the peroxidase-like activity owing to the high N doping. N-doped C-PDANTs could catalyze the reduction of H2O2 to produce OH● radicals, which contributed to the oxidation of 3,3’, 5,5’-tetramethylbenzidine (TMB) substrates. Moreover, the catalytic mechanism of N-doped C-PDANTs was further revealed by electrochemical measurements. N-doped C-PDANTs with pyridinic N and graphitic N compositions possess the capability to accelerate the electron transfer, thus facilitating the reduction of H2O2. The application of N-doped C-PDANTs were demonstrated in the sensitive detection of glutathione (GSH) in serum samples. Therefore, the present study provides a facile way to prepared peroxidase-like nanomaterials with high specificity.
dc.language	English
dc.publisher	ELSEVIER SCIENCE SA
dc.relation.ispartof	Sensors and Actuators, B: Chemical
dc.relation.isbasedon	10.1016/j.snb.2021.129987
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0205 Optical Physics, 0301 Analytical Chemistry, 0912 Materials Engineering
dc.subject.classification	Analytical Chemistry
dc.title	Improved the specificity of peroxidase-like carbonized polydopamine nanotubes with high nitrogen doping for glutathione detection
dc.type	Journal Article
utslib.citation.volume	341
utslib.for	0205 Optical Physics
utslib.for	0301 Analytical Chemistry
utslib.for	0912 Materials Engineering
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CCET - Centre for Clean Energy Technology
utslib.copyright.status	closed_access	*
dc.date.updated	2022-02-06T22:31:54Z
pubs.publication-status	Published
pubs.volume	341

Abstract:

The introduction of nitrogen heteroatoms into enzyme-like carbon materials is an effective strategy to enhance both catalytic activity and specificity. Herein, we described the preparation of the carbonized polydopamine nanotubes (C-DPANTs) using sacrificial halloysite nanotubes (HNTs) templates. The resulting nitrogen doped C-PDANTs (N-doped C-PDANTs) exhibit solely the peroxidase-like activity owing to the high N doping. N-doped C-PDANTs could catalyze the reduction of H2O2 to produce OH● radicals, which contributed to the oxidation of 3,3’, 5,5’-tetramethylbenzidine (TMB) substrates. Moreover, the catalytic mechanism of N-doped C-PDANTs was further revealed by electrochemical measurements. N-doped C-PDANTs with pyridinic N and graphitic N compositions possess the capability to accelerate the electron transfer, thus facilitating the reduction of H2O2. The application of N-doped C-PDANTs were demonstrated in the sensitive detection of glutathione (GSH) in serum samples. Therefore, the present study provides a facile way to prepared peroxidase-like nanomaterials with high specificity.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/154228