The bacterial divisome: more than a ring?

Söderström, B; Daley, DO

The bacterial divisome: more than a ring?

Söderström, B Daley, DO

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Publisher:: SPRINGER
Publication Type:: Journal Article
Citation:: Curr Genet, 2017, 63, (2), pp. 161-164
Issue Date:: 2017-05

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Field	Value	Language
dc.contributor.author	Söderström, B
dc.contributor.author	Daley, DO
dc.date.accessioned	2022-03-31T06:35:50Z
dc.date.available	2016-07-01
dc.date.available	2022-03-31T06:35:50Z
dc.date.issued	2017-05
dc.identifier.citation	Curr Genet, 2017, 63, (2), pp. 161-164
dc.identifier.issn	0172-8083
dc.identifier.issn	1432-0983
dc.identifier.uri	http://hdl.handle.net/10453/155793
dc.description.abstract	Bacterial cells are critically dependent on their ability to divide. The process of division is carried out by a large and highly dynamic molecular machine, known as the divisome. An understanding of the divisomes' architecture is highly sought after, as it is essential for understanding molecular mechanisms and potentially designing antibiotic molecules that curb bacterial growth. Our current view, which is mainly based on high-resolution imaging of Escherichia coli, is that it is a patchy ring or toroid structure. However, recent super-resolution imaging has shown that the toroid structure contains at least three concentric rings, each containing a different set of proteins. Thus, the emerging picture is that the divisome has different functional modules that are spatially separated in concentric rings.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	SPRINGER
dc.relation.ispartof	Curr Genet
dc.relation.isbasedon	10.1007/s00294-016-0630-2
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0604 Genetics, 0605 Microbiology
dc.subject.classification	Microbiology
dc.subject.mesh	Cell Division
dc.subject.mesh	Escherichia coli
dc.subject.mesh	Escherichia coli Proteins
dc.subject.mesh	Green Fluorescent Proteins
dc.subject.mesh	Luminescent Proteins
dc.subject.mesh	Microscopy, Fluorescence
dc.subject.mesh	Models, Biological
dc.subject.mesh	Multiprotein Complexes
dc.subject.mesh	Time-Lapse Imaging
dc.subject.mesh	Escherichia coli
dc.subject.mesh	Multiprotein Complexes
dc.subject.mesh	Escherichia coli Proteins
dc.subject.mesh	Luminescent Proteins
dc.subject.mesh	Green Fluorescent Proteins
dc.subject.mesh	Microscopy, Fluorescence
dc.subject.mesh	Cell Division
dc.subject.mesh	Models, Biological
dc.subject.mesh	Time-Lapse Imaging
dc.title	The bacterial divisome: more than a ring?
dc.type	Journal Article
utslib.citation.volume	63
utslib.location.activity	United States
utslib.for	0604 Genetics
utslib.for	0605 Microbiology
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - ithree - Institute of Infection, Immunity and Innovation
utslib.copyright.status	closed_access	*
dc.date.updated	2022-03-31T06:35:49Z
pubs.issue	2
pubs.publication-status	Published
pubs.volume	63
utslib.citation.issue	2

Abstract:

Bacterial cells are critically dependent on their ability to divide. The process of division is carried out by a large and highly dynamic molecular machine, known as the divisome. An understanding of the divisomes' architecture is highly sought after, as it is essential for understanding molecular mechanisms and potentially designing antibiotic molecules that curb bacterial growth. Our current view, which is mainly based on high-resolution imaging of Escherichia coli, is that it is a patchy ring or toroid structure. However, recent super-resolution imaging has shown that the toroid structure contains at least three concentric rings, each containing a different set of proteins. Thus, the emerging picture is that the divisome has different functional modules that are spatially separated in concentric rings.

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http://hdl.handle.net/10453/155793