Combination of cytosine deaminase with uracil phosphoribosyl transferase leads to local and distant bystander effects against RM1 prostate cancer in mice

John Wiley & Sons Ltd
Publication Type:
Journal Article
Journal Of Gene Medicine, 2006, 8 (9), pp. 1086 - 1096
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Background We aimed to evaluate the efficacy of gene-directed enzyme-prodrug therapy (GDEPT) using cytosine deaminase in combination with uracil phosphoribosyl transferase (CDUPRT) against intraprostatic mouse androgen-refractory prostate (RM1) tumors in
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