Biophotonics characterization of upconversion nanoparticles

Ding, Lei

Biophotonics characterization of upconversion nanoparticles

Ding, Lei

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Publication Type:: Thesis
Issue Date:: 2022

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Field	Value	Language
dc.contributor.author	Ding, Lei
dc.date.accessioned	2022-11-25T04:22:44Z
dc.date.available	2022-11-25T04:22:44Z
dc.date.issued	2022
dc.identifier.uri	http://hdl.handle.net/10453/163748
dc.description	University of Technology Sydney. Faculty of Science.	en_US.UTF-8
dc.description.abstract	Upconversion materials have attracted enormous attention for a broad range of applications in biological imaging, energy-related light harvesting, and sensing, due to their unique physicochemical properties. However, the comprehensive understanding and characterization of upconversion nanoparticles for novel applications remain challenging. In this thesis, we set four goals to refresh the present characterization and provide a wider and deeper cognition of these upconversion nanoparticles. After the delicate design of optical setups and nanomaterials, we realized the super resolution enhancement, optical force sensitivity improvement, Rayleigh scattering modulation, and a new water-soluble molecular upconversion probe. Experimentally and theoretically, we upgrade the nanoscopy by exploiting the unique nonlinearity of upconversion nanoparticles using conventional confocal microscopy. We realize three-dimensional attoNewton-level optical force of optical via revolutionizing the configuration, data collection and accuracy analysis based on the property of upconversion nanoparticles. We refresh the morphology-independent method of engineering Rayleigh scattering at the nanoscale level based on the resonance effect of upconversion nanoparticles. We develop water-soluble molecular upconversion materials based on the ionic equilibrium of upconversion dyes. Based on the improved characterization of upconversion materials, as well as the technologies, we anticipate the potential applications in future, such as, deep tissue imaging, monitoring the interaction in the limit region (e.g., attoNewton level), and multiplexed scattering microscopy of cell dynamics.	en_US.UTF-8
dc.format	Thesis (PhD)
dc.language.iso	en_US	en_US.UTF-8
dc.relation	https://opus.lib.uts.edu.au/bitstream/10453/163748/2/02whole.pdf
dc.rights	The author owns the copyright in this thesis including all reproduction and reuse rights for the work. The work may not be altered without the permission of the copyright owner. Attribution is essential when quoting or paraphrasing from this thesis.
dc.rights	au.edu.uts.lib/ppc
dc.rights	info:eu-repo/semantics/openAccess
dc.title	Biophotonics characterization of upconversion nanoparticles	en_US.UTF-8
dc.type	Thesis
utslib.copyright.status	open_access	*

Abstract:

Upconversion materials have attracted enormous attention for a broad range of applications in biological imaging, energy-related light harvesting, and sensing, due to their unique physicochemical properties. However, the comprehensive understanding and characterization of upconversion nanoparticles for novel applications remain challenging. In this thesis, we set four goals to refresh the present characterization and provide a wider and deeper cognition of these upconversion nanoparticles. After the delicate design of optical setups and nanomaterials, we realized the super resolution enhancement, optical force sensitivity improvement, Rayleigh scattering modulation, and a new water-soluble molecular upconversion probe. Experimentally and theoretically, we upgrade the nanoscopy by exploiting the unique nonlinearity of upconversion nanoparticles using conventional confocal microscopy. We realize three-dimensional attoNewton-level optical force of optical via revolutionizing the configuration, data collection and accuracy analysis based on the property of upconversion nanoparticles. We refresh the morphology-independent method of engineering Rayleigh scattering at the nanoscale level based on the resonance effect of upconversion nanoparticles. We develop water-soluble molecular upconversion materials based on the ionic equilibrium of upconversion dyes. Based on the improved characterization of upconversion materials, as well as the technologies, we anticipate the potential applications in future, such as, deep tissue imaging, monitoring the interaction in the limit region (e.g., attoNewton level), and multiplexed scattering microscopy of cell dynamics.

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http://hdl.handle.net/10453/163748