Spirometry for chronic obstructive pulmonary disease due to inhalation of smoke from indoor fires used for cooking and heating
- Publisher:
- John Wiley & Sons, Inc.
- Publication Type:
- Chapter
- Citation:
- Revolutionizing Tropical Medicine: Point-of-Care Tests, New Imaging Technologies and Digital Health, 2019, pp. 306-326
- Issue Date:
- 2019-05-31
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| Filename | Description | Size | |||
|---|---|---|---|---|---|
| Revolutionizing_Tropical_Medicine_Point-Of-Care_Te..._----_(Chapter_20_Spirometry_for_Chronic_Obstructive_Pulmonary_Disease_Due_to...).pdf | Published version | 749.45 kB |
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Almost one third of the world's population uses biomass fuel for cooking and heating, contributing significantly to exposure from indoor air pollution. Common biomass fuels include wood, dung and crop residues. Burning of biomass fuels in poorly ventilated indoor household areas leads to the emission of toxic particulate matter and volatile gasses which, when inhaled, result in inflammation and oxidative stress in the lungs. This toxicity can, like that of cigarette smoking, lead to the development of chronic obstructive pulmonary disease (COPD), which is characterized by exertional breathlessness, cough and sputum production, with the presence of chronic airflow obstruction on spirometry. Inflammation and oxidative stress have been identified as key cellular and molecular mechanisms in the pathogenesis of COPD. Cigarette smoke exposure is considered to be the main risk factor for COPD. Spirometry testing is recognized as the gold standard for diagnosing and grading the severity of airflow obstruction.
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