NIR-II emissive properties of 808 nm-excited lanthanide-doped nanoparticles for multiplexed in vivo imaging

Liao, J; Yang, L; Wu, S; Yang, Z; Zhou, J; Jin, D; Guan, M

NIR-II emissive properties of 808 nm-excited lanthanide-doped nanoparticles for multiplexed in vivo imaging

Liao, J

Yang, L Wu, S Yang, Z Zhou, J

Jin, D

Guan, M

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Publisher:: ELSEVIER
Publication Type:: Journal Article
Citation:: Journal of Luminescence, 2022, 242
Issue Date:: 2022-02-01

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Field	Value	Language
dc.contributor.author	Liao, J https://orcid.org/0000-0003-0616-4762
dc.contributor.author	Yang, L
dc.contributor.author	Wu, S
dc.contributor.author	Yang, Z
dc.contributor.author	Zhou, J https://orcid.org/0000-0002-0605-5745
dc.contributor.author	Jin, D https://orcid.org/0000-0003-1046-2666
dc.contributor.author	Guan, M
dc.date.accessioned	2023-01-30T03:22:25Z
dc.date.available	2023-01-30T03:22:25Z
dc.date.issued	2022-02-01
dc.identifier.citation	Journal of Luminescence, 2022, 242
dc.identifier.issn	0022-2313
dc.identifier.issn	1872-7883
dc.identifier.uri	http://hdl.handle.net/10453/165579
dc.description.abstract	The second near-infrared window (1000–1700 nm, NIR-II) emissive lanthanide-doped nanoparticles excited by 808 nm laser are ideal for in vivo bioimaging due to their non-heating excitation. The study of 808 nm excited lanthanide-doped nanoparticles not only provides high-quality NIR-II imaging but also can promote in vivo multiplexed bioimaging under single excitation. Herein, we prepared three sets of typical 808 nm excited lanthanide-doped nanoparticles (NaYF4: Nd3+@NaYF4, NaErF4@NaYF4, and NaYbF4: Er3+/Ce3+@NaYbF4@NaYF4: Yb3+/Nd3+) and then systematically compared their optical properties in the NIR-II window. Furthermore, we prepared water-soluble and biocompatible nanoprobes and achieved multiplexed NIR-II in vivo imaging in mice under single 808 nm excitation. These results highlight the potential of 808 nm excited lanthanide probes for physiological studies and biomedical applications.
dc.language	English
dc.publisher	ELSEVIER
dc.relation	National Natural Science Foundation of China61729501
dc.relation.ispartof	Journal of Luminescence
dc.relation.isbasedon	10.1016/j.jlumin.2021.118597
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0205 Optical Physics, 0306 Physical Chemistry (incl. Structural)
dc.subject.classification	Applied Physics
dc.title	NIR-II emissive properties of 808 nm-excited lanthanide-doped nanoparticles for multiplexed in vivo imaging
dc.type	Journal Article
utslib.citation.volume	242
utslib.for	0205 Optical Physics
utslib.for	0306 Physical Chemistry (incl. Structural)
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
utslib.copyright.status	closed_access	*
dc.date.updated	2023-01-30T03:22:23Z
pubs.publication-status	Published
pubs.volume	242

Abstract:

The second near-infrared window (1000–1700 nm, NIR-II) emissive lanthanide-doped nanoparticles excited by 808 nm laser are ideal for in vivo bioimaging due to their non-heating excitation. The study of 808 nm excited lanthanide-doped nanoparticles not only provides high-quality NIR-II imaging but also can promote in vivo multiplexed bioimaging under single excitation. Herein, we prepared three sets of typical 808 nm excited lanthanide-doped nanoparticles (NaYF4: Nd3+@NaYF4, NaErF4@NaYF4, and NaYbF4: Er3+/Ce3+@NaYbF4@NaYF4: Yb3+/Nd3+) and then systematically compared their optical properties in the NIR-II window. Furthermore, we prepared water-soluble and biocompatible nanoprobes and achieved multiplexed NIR-II in vivo imaging in mice under single 808 nm excitation. These results highlight the potential of 808 nm excited lanthanide probes for physiological studies and biomedical applications.

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http://hdl.handle.net/10453/165579