Photodynamic viral inactivation assisted by photosensitizers

Sadraeian, M; Zhang, L; Aavani, F; Biazar, E; Jin, D

Photodynamic viral inactivation assisted by photosensitizers

Sadraeian, M

Zhang, L Aavani, F Biazar, E Jin, D

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Publisher:: ELSEVIER
Publication Type:: Journal Article
Citation:: Materials Today Physics, 2022, 28
Issue Date:: 2022-11-01

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Field	Value	Language
dc.contributor.author	Sadraeian, M https://orcid.org/0000-0002-7384-2247
dc.contributor.author	Zhang, L
dc.contributor.author	Aavani, F
dc.contributor.author	Biazar, E
dc.contributor.author	Jin, D https://orcid.org/0000-0003-1046-2666
dc.date.accessioned	2023-01-30T03:27:44Z
dc.date.available	2023-01-30T03:27:44Z
dc.date.issued	2022-11-01
dc.identifier.citation	Materials Today Physics, 2022, 28
dc.identifier.issn	2542-5293
dc.identifier.issn	2542-5293
dc.identifier.uri	http://hdl.handle.net/10453/165580
dc.description.abstract	The deadly viruses, which are spreading worldwide at an alarming rate, are a major challenge for the life sciences. More efficient and cost-effective methods with fewer side effects can provide a good alternative to traditional drug-based methods. Currently, physical phenomena such as light in the form of photodynamic action are increasingly being used to inactivate viruses. Photodynamic inactivation (PDI) uses a photosensitizer (PS), light, and oxygen to generate reactive oxygen species (ROS) to inactivate microorganisms. This article reviews the use of existing PSs, as one of the essential anti-viral agents, and introduces new materials and strategies combined with PDI. Physiochemical properties of PSs and their role in interaction with virus components are discussed. Furthermore, the effectiveness of optical sensitizers with radiation methods to inactivate viruses is highlighted.
dc.language	English
dc.publisher	ELSEVIER
dc.relation	http://purl.org/au-research/grants/arc/FL210100180
dc.relation.ispartof	Materials Today Physics
dc.relation.isbasedon	10.1016/j.mtphys.2022.100882
dc.rights	info:eu-repo/semantics/closedAccess
dc.title	Photodynamic viral inactivation assisted by photosensitizers
dc.type	Journal Article
utslib.citation.volume	28
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
utslib.copyright.status	closed_access	*
dc.date.updated	2023-01-30T03:27:42Z
pubs.publication-status	Published
pubs.volume	28

Abstract:

The deadly viruses, which are spreading worldwide at an alarming rate, are a major challenge for the life sciences. More efficient and cost-effective methods with fewer side effects can provide a good alternative to traditional drug-based methods. Currently, physical phenomena such as light in the form of photodynamic action are increasingly being used to inactivate viruses. Photodynamic inactivation (PDI) uses a photosensitizer (PS), light, and oxygen to generate reactive oxygen species (ROS) to inactivate microorganisms. This article reviews the use of existing PSs, as one of the essential anti-viral agents, and introduces new materials and strategies combined with PDI. Physiochemical properties of PSs and their role in interaction with virus components are discussed. Furthermore, the effectiveness of optical sensitizers with radiation methods to inactivate viruses is highlighted.

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http://hdl.handle.net/10453/165580