The use of lipids from textiles as soft-tissue biomarkers of human decomposition.

Collins, S; Stuart, B; Ueland, M

The use of lipids from textiles as soft-tissue biomarkers of human decomposition.

Collins, S Stuart, B

Ueland, M

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Publisher:: Elsevier BV
Publication Type:: Journal Article
Citation:: Forensic Sci Int, 2022, 343, pp. 111547
Issue Date:: 2022-12-24

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Field	Value	Language
dc.contributor.author	Collins, S
dc.contributor.author	Stuart, B https://orcid.org/0000-0001-9540-4435
dc.contributor.author	Ueland, M https://orcid.org/0000-0002-9155-3502
dc.date.accessioned	2023-02-03T03:12:25Z
dc.date.available	2022-12-22
dc.date.available	2023-02-03T03:12:25Z
dc.date.issued	2022-12-24
dc.identifier.citation	Forensic Sci Int, 2022, 343, pp. 111547
dc.identifier.issn	0379-0738
dc.identifier.issn	1872-6283
dc.identifier.uri	http://hdl.handle.net/10453/165880
dc.description.abstract	The ability to determine the post-mortem interval (PMI) in complex death investigations involving human remains, is a vital task faced by law enforcement. Establishing the PMI in a case can significantly aid in the reconstruction of forensically relevant events surrounding that death. However, due to the complexities surrounding the decomposition of human remains, the determination of the PMI still remains a challenge in some cases. Thus, the identification of biomarkers of human decomposition are an emerging, and essential, area of research. Previous studies have also demonstrated great success in the use of textiles as a host to indirectly capture decomposition by-products. This study reports the successful adaptation and optimisation of an analytical chemical workflow for the targeted analysis of lipids from textiles associated with decomposing human remains using gas-chromatography (GC) coupled with tandem mass spectrometry (MS/MS). This study discusses novel information regarding the complex challenges of matrix effects observed with decomposition samples. In addition, the first lipid profiles obtained from textiles associated with two decomposing human donors from the Australian Facility for Taphonomic Experimental Research (AFTER) using GC-MS/MS are presented.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Elsevier BV
dc.relation	http://purl.org/au-research/grants/arc/DE210100494
dc.relation	http://purl.org/au-research/grants/arc/LE150100015
dc.relation.ispartof	Forensic Sci Int
dc.relation.isbasedon	10.1016/j.forsciint.2022.111547
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject.classification	Legal & Forensic Medicine
dc.title	The use of lipids from textiles as soft-tissue biomarkers of human decomposition.
dc.type	Journal Article
utslib.citation.volume	343
utslib.location.activity	Ireland
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - CFS - Centre for Forensic Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
utslib.copyright.status	closed_access	*
dc.date.updated	2023-02-03T03:12:22Z
pubs.publication-status	Published online
pubs.volume	343

Abstract:

The ability to determine the post-mortem interval (PMI) in complex death investigations involving human remains, is a vital task faced by law enforcement. Establishing the PMI in a case can significantly aid in the reconstruction of forensically relevant events surrounding that death. However, due to the complexities surrounding the decomposition of human remains, the determination of the PMI still remains a challenge in some cases. Thus, the identification of biomarkers of human decomposition are an emerging, and essential, area of research. Previous studies have also demonstrated great success in the use of textiles as a host to indirectly capture decomposition by-products. This study reports the successful adaptation and optimisation of an analytical chemical workflow for the targeted analysis of lipids from textiles associated with decomposing human remains using gas-chromatography (GC) coupled with tandem mass spectrometry (MS/MS). This study discusses novel information regarding the complex challenges of matrix effects observed with decomposition samples. In addition, the first lipid profiles obtained from textiles associated with two decomposing human donors from the Australian Facility for Taphonomic Experimental Research (AFTER) using GC-MS/MS are presented.

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http://hdl.handle.net/10453/165880