Autosomal short tandem repeat (STR) profiling of human skeletal remains

Watherston, J; Ward, J

Autosomal short tandem repeat (STR) profiling of human skeletal remains

Watherston, J Ward, J

Permalink

Publisher:: Elsevier
Publication Type:: Chapter
Citation:: Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies, 2023, pp. 167-197
Issue Date:: 2023-01-01

Closed Access

	Filename	Description	Size
	20578928_10387051420005671.pdf	Published version	1.7 MB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Watherston, J
dc.contributor.author	Ward, J https://orcid.org/0000-0001-9359-9806
dc.date.accessioned	2023-04-10T22:38:52Z
dc.date.available	2023-04-10T22:38:52Z
dc.date.issued	2023-01-01
dc.identifier.citation	Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies, 2023, pp. 167-197
dc.identifier.isbn	9780128163696
dc.identifier.uri	http://hdl.handle.net/10453/169400
dc.description.abstract	This chapter introduces autosomal short tandem repeats (STRs) and their use as the most popular genetic marker for human identification. It explains the characteristics of STR loci that make them suitable for forensic use and lists the core STR loci currently used for DNA profiling. Commercial STR multiplexes and thermal cycling instruments commonly used by forensic laboratories are presented, and the applicability of each for profiling of human skeletal remains is discussed. PCR conditions that can be modified to improve STR profiling results from challenging human skeletal samples are also detailed. Finally, technologies that facilitate high-throughput and/or rapid STR profiling for large-scale identification efforts are explored.
dc.format.extent	24
dc.language	en
dc.publisher	Elsevier
dc.relation.ispartof	Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies
dc.relation.isbasedon	10.1016/B978-0-12-815766-4.00008-X
dc.rights	info:eu-repo/semantics/closedAccess
dc.title	Autosomal short tandem repeat (STR) profiling of human skeletal remains
dc.type	Chapter
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - CFS - Centre for Forensic Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2023-04-10T22:38:51Z
pubs.place-of-publication	The Netherlands
pubs.publication-status	Published
dc.location	The Netherlands

Abstract:

This chapter introduces autosomal short tandem repeats (STRs) and their use as the most popular genetic marker for human identification. It explains the characteristics of STR loci that make them suitable for forensic use and lists the core STR loci currently used for DNA profiling. Commercial STR multiplexes and thermal cycling instruments commonly used by forensic laboratories are presented, and the applicability of each for profiling of human skeletal remains is discussed. PCR conditions that can be modified to improve STR profiling results from challenging human skeletal samples are also detailed. Finally, technologies that facilitate high-throughput and/or rapid STR profiling for large-scale identification efforts are explored.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/169400