Mechanisms of body weight reduction and metabolic syndrome alleviation by tea.

Yang, CS; Zhang, J; Zhang, L; Huang, J; Wang, Y

Mechanisms of body weight reduction and metabolic syndrome alleviation by tea.

Yang, CS Zhang, J Zhang, L

Huang, J Wang, Y

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Publisher:: Wiley
Publication Type:: Journal Article
Citation:: Mol Nutr Food Res, 2016, 60, (1), pp. 160-174
Issue Date:: 2016-01

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Field	Value	Language
dc.contributor.author	Yang, CS
dc.contributor.author	Zhang, J
dc.contributor.author	Zhang, L https://orcid.org/0000-0003-0641-2383
dc.contributor.author	Huang, J
dc.contributor.author	Wang, Y
dc.date.accessioned	2023-04-19T23:24:19Z
dc.date.available	2015-11-06
dc.date.available	2023-04-19T23:24:19Z
dc.date.issued	2016-01
dc.identifier.citation	Mol Nutr Food Res, 2016, 60, (1), pp. 160-174
dc.identifier.issn	1613-4125
dc.identifier.issn	1613-4133
dc.identifier.uri	http://hdl.handle.net/10453/169997
dc.description.abstract	Tea, a popular beverage made from leaves of the plant Camellia sinensis, has been shown to reduce body weight, alleviate metabolic syndrome, and prevent diabetes and cardiovascular diseases in animal models and humans. Such beneficial effects have generally been observed in most human studies when the level of tea consumption was three to four cups (600-900 mg tea catechins) or more per day. Green tea is more effective than black tea. In spite of numerous studies, the fundamental mechanisms for these actions still remain unclear. From a review of the literature, we propose that the two major mechanisms are: (i) decreasing absorption of lipids and proteins by tea constituents in the intestine, thus reducing calorie intake; and (ii) activating AMP-activated protein kinase by tea polyphenols that are bioavailable in the liver, skeletal muscle, and adipose tissues. The relative importance of these two mechanisms depends on the types of tea and diet consumed by individuals. The activated AMP-activated protein kinase would decrease gluconeogenesis and fatty acid synthesis and increase catabolism, leading to body weight reduction and metabolic syndrome alleviation. Other mechanisms and the health relevance of these beneficial effects of tea consumption remain to be further investigated.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Wiley
dc.relation.ispartof	Mol Nutr Food Res
dc.relation.isbasedon	10.1002/mnfr.201500428
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0908 Food Sciences, 1111 Nutrition and Dietetics, 1117 Public Health and Health Services
dc.subject.classification	Food Science
dc.subject.classification	Nutrition & Dietetics
dc.subject.mesh	AMP-Activated Protein Kinases
dc.subject.mesh	Adipose Tissue
dc.subject.mesh	Animals
dc.subject.mesh	Camellia sinensis
dc.subject.mesh	Cardiovascular Diseases
dc.subject.mesh	Catechin
dc.subject.mesh	Diabetes Mellitus, Type 2
dc.subject.mesh	Disease Models, Animal
dc.subject.mesh	Humans
dc.subject.mesh	Liver
dc.subject.mesh	Meta-Analysis as Topic
dc.subject.mesh	Metabolic Syndrome
dc.subject.mesh	Muscle, Skeletal
dc.subject.mesh	Plant Leaves
dc.subject.mesh	Polyphenols
dc.subject.mesh	Randomized Controlled Trials as Topic
dc.subject.mesh	Risk Factors
dc.subject.mesh	Tea
dc.subject.mesh	Weight Loss
dc.subject.mesh	Muscle, Skeletal
dc.subject.mesh	Liver
dc.subject.mesh	Adipose Tissue
dc.subject.mesh	Animals
dc.subject.mesh	Humans
dc.subject.mesh	Camellia sinensis
dc.subject.mesh	Plant Leaves
dc.subject.mesh	Cardiovascular Diseases
dc.subject.mesh	Diabetes Mellitus, Type 2
dc.subject.mesh	Disease Models, Animal
dc.subject.mesh	Weight Loss
dc.subject.mesh	Catechin
dc.subject.mesh	Risk Factors
dc.subject.mesh	Tea
dc.subject.mesh	Meta-Analysis as Topic
dc.subject.mesh	Randomized Controlled Trials as Topic
dc.subject.mesh	AMP-Activated Protein Kinases
dc.subject.mesh	Polyphenols
dc.subject.mesh	Metabolic Syndrome
dc.subject.mesh	AMP-Activated Protein Kinases
dc.subject.mesh	Adipose Tissue
dc.subject.mesh	Animals
dc.subject.mesh	Camellia sinensis
dc.subject.mesh	Cardiovascular Diseases
dc.subject.mesh	Catechin
dc.subject.mesh	Diabetes Mellitus, Type 2
dc.subject.mesh	Disease Models, Animal
dc.subject.mesh	Humans
dc.subject.mesh	Liver
dc.subject.mesh	Meta-Analysis as Topic
dc.subject.mesh	Metabolic Syndrome
dc.subject.mesh	Muscle, Skeletal
dc.subject.mesh	Plant Leaves
dc.subject.mesh	Polyphenols
dc.subject.mesh	Randomized Controlled Trials as Topic
dc.subject.mesh	Risk Factors
dc.subject.mesh	Tea
dc.subject.mesh	Weight Loss
dc.title	Mechanisms of body weight reduction and metabolic syndrome alleviation by tea.
dc.type	Journal Article
utslib.citation.volume	60
utslib.location.activity	Germany
utslib.for	0908 Food Sciences
utslib.for	1111 Nutrition and Dietetics
utslib.for	1117 Public Health and Health Services
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
utslib.copyright.status	closed_access	*
dc.date.updated	2023-04-19T23:24:15Z
pubs.issue	1
pubs.publication-status	Published
pubs.volume	60
utslib.citation.issue	1

Abstract:

Tea, a popular beverage made from leaves of the plant Camellia sinensis, has been shown to reduce body weight, alleviate metabolic syndrome, and prevent diabetes and cardiovascular diseases in animal models and humans. Such beneficial effects have generally been observed in most human studies when the level of tea consumption was three to four cups (600-900 mg tea catechins) or more per day. Green tea is more effective than black tea. In spite of numerous studies, the fundamental mechanisms for these actions still remain unclear. From a review of the literature, we propose that the two major mechanisms are: (i) decreasing absorption of lipids and proteins by tea constituents in the intestine, thus reducing calorie intake; and (ii) activating AMP-activated protein kinase by tea polyphenols that are bioavailable in the liver, skeletal muscle, and adipose tissues. The relative importance of these two mechanisms depends on the types of tea and diet consumed by individuals. The activated AMP-activated protein kinase would decrease gluconeogenesis and fatty acid synthesis and increase catabolism, leading to body weight reduction and metabolic syndrome alleviation. Other mechanisms and the health relevance of these beneficial effects of tea consumption remain to be further investigated.

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http://hdl.handle.net/10453/169997