Myopia Research: Improving the Quantification of Risk Factors

Publication Type:
Thesis
Issue Date:
2022
Full metadata record
Myopia has become a major concern for eye care professionals. The increasing prevalence of high myopia suggest that there will be an increased risk of sight threatening pathologies that conventional treatment does not prevent. The myopia epidemic and looming rates of associated visual impairment, stimulated further studies of the aetiology of myopia, in order to develop more effective preventive intervention strategies. This thesis aims to improve study methods in myopia research by identifying accurate and reliable tools for capturing behavioural exposures and by investigating an effective non-invasive means to relate these exposures to refractive changes. Evidence was provided for the presence of measurement errors occurring at several levels between commonly used portable light data logging devices used to objectively capture time outdoors. Additionally, the utility of an alternative method of determining refractive error and myopia risk was identified using ocular biometrics. Together these findings allow for more detailed measurements of causal and explanatory variables in myopia epidemiological studies. These findings also indicate a need for future methodological standardisation in myopia research, enabling more effective and reliable studies to further investigate the various relationships between behavioural environmental risk factors and myopia.
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