Protozoan predation as a driver of diversity and virulence in bacterial biofilms.

Hoque, MM; Espinoza-Vergara, G; McDougald, D

Protozoan predation as a driver of diversity and virulence in bacterial biofilms.

Hoque, MM Espinoza-Vergara, G McDougald, D

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Publisher:: OXFORD UNIV PRESS
Publication Type:: Journal Article
Citation:: FEMS Microbiol Rev, 2023, 47, (4), pp. fuad040
Issue Date:: 2023-07-05

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Field	Value	Language
dc.contributor.author	Hoque, MM
dc.contributor.author	Espinoza-Vergara, G
dc.contributor.author	McDougald, D
dc.date.accessioned	2024-01-10T23:42:38Z
dc.date.available	2023-07-07
dc.date.available	2024-01-10T23:42:38Z
dc.date.issued	2023-07-05
dc.identifier.citation	FEMS Microbiol Rev, 2023, 47, (4), pp. fuad040
dc.identifier.issn	0168-6445
dc.identifier.issn	1574-6976
dc.identifier.uri	http://hdl.handle.net/10453/174249
dc.description.abstract	Protozoa are eukaryotic organisms that play a crucial role in nutrient cycling and maintaining balance in the food web. Predation, symbiosis and parasitism are three types of interactions between protozoa and bacteria. However, not all bacterial species are equally susceptible to protozoan predation as many are capable of defending against predation in numerous ways and may even establish either a symbiotic or parasitic life-style. Biofilm formation is one such mechanism by which bacteria can survive predation. Structural and chemical components of biofilms enhance resistance to predation compared to their planktonic counterparts. Predation on biofilms gives rise to phenotypic and genetic heterogeneity in prey that leads to trade-offs in virulence in other eukaryotes. Recent advances, using molecular and genomics techniques, allow us to generate new information about the interactions of protozoa and biofilms of prey bacteria. This review presents the current state of the field on impacts of protozoan predation on biofilms. We provide an overview of newly gathered insights into (i) molecular mechanisms of predation resistance in biofilms, (ii) phenotypic and genetic diversification of prey bacteria, and (iii) evolution of virulence as a consequence of protozoan predation on biofilms.
dc.format	Print
dc.language	eng
dc.publisher	OXFORD UNIV PRESS
dc.relation	http://purl.org/au-research/grants/arc/DP170100453
dc.relation.ispartof	FEMS Microbiol Rev
dc.relation.isbasedon	10.1093/femsre/fuad040
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0605 Microbiology, 1108 Medical Microbiology
dc.subject.classification	Microbiology
dc.subject.classification	3107 Microbiology
dc.subject.mesh	Animals
dc.subject.mesh	Virulence
dc.subject.mesh	Predatory Behavior
dc.subject.mesh	Eukaryota
dc.subject.mesh	Bacteria
dc.subject.mesh	Biofilms
dc.subject.mesh	Animals
dc.subject.mesh	Bacteria
dc.subject.mesh	Biofilms
dc.subject.mesh	Predatory Behavior
dc.subject.mesh	Virulence
dc.subject.mesh	Eukaryota
dc.subject.mesh	Animals
dc.subject.mesh	Virulence
dc.subject.mesh	Predatory Behavior
dc.subject.mesh	Eukaryota
dc.subject.mesh	Bacteria
dc.subject.mesh	Biofilms
dc.title	Protozoan predation as a driver of diversity and virulence in bacterial biofilms.
dc.type	Journal Article
utslib.citation.volume	47
utslib.location.activity	England
utslib.for	0605 Microbiology
utslib.for	1108 Medical Microbiology
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - AIMI - Australian Institute for Microbiology & Infection
utslib.copyright.status	closed_access	*
dc.date.updated	2024-01-10T23:42:36Z
pubs.issue	4
pubs.publication-status	Published
pubs.volume	47
utslib.citation.issue	4

Abstract:

Protozoa are eukaryotic organisms that play a crucial role in nutrient cycling and maintaining balance in the food web. Predation, symbiosis and parasitism are three types of interactions between protozoa and bacteria. However, not all bacterial species are equally susceptible to protozoan predation as many are capable of defending against predation in numerous ways and may even establish either a symbiotic or parasitic life-style. Biofilm formation is one such mechanism by which bacteria can survive predation. Structural and chemical components of biofilms enhance resistance to predation compared to their planktonic counterparts. Predation on biofilms gives rise to phenotypic and genetic heterogeneity in prey that leads to trade-offs in virulence in other eukaryotes. Recent advances, using molecular and genomics techniques, allow us to generate new information about the interactions of protozoa and biofilms of prey bacteria. This review presents the current state of the field on impacts of protozoan predation on biofilms. We provide an overview of newly gathered insights into (i) molecular mechanisms of predation resistance in biofilms, (ii) phenotypic and genetic diversification of prey bacteria, and (iii) evolution of virulence as a consequence of protozoan predation on biofilms.

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http://hdl.handle.net/10453/174249