The Effect of Benzyl Alcohol on the Voltage-Current Characteristics of Tethered Lipid Bilayers.

Alobeedallah, H; Cornell, B; Ghazal, M; Coster, H

The Effect of Benzyl Alcohol on the Voltage-Current Characteristics of Tethered Lipid Bilayers.

Alobeedallah, H Cornell, B

Ghazal, M Coster, H

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Publisher:: Springer Nature
Publication Type:: Journal Article
Citation:: J Membr Biol, 2023, 256, (4-6), pp. 423-431
Issue Date:: 2023-12

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Field	Value	Language
dc.contributor.author	Alobeedallah, H
dc.contributor.author	Cornell, B https://orcid.org/0000-0003-4166-3241
dc.contributor.author	Ghazal, M
dc.contributor.author	Coster, H
dc.date.accessioned	2024-01-16T00:30:01Z
dc.date.available	2023-08-21
dc.date.available	2024-01-16T00:30:01Z
dc.date.issued	2023-12
dc.identifier.citation	J Membr Biol, 2023, 256, (4-6), pp. 423-431
dc.identifier.issn	0022-2631
dc.identifier.issn	1432-1424
dc.identifier.uri	http://hdl.handle.net/10453/174515
dc.description.abstract	In this study a lipid bilayer membrane model was used in which the bilayer is tethered to a solid substrate with molecular tethers. Voltage-current (V-I) measurements of the tethered bilayer membranes (tBLM) and tBLM with benzyl alcohol (BZA) incorporated in their structures, were measured using triangular voltage ramps of 0-500 mV. The temperature dependence of the conductance deduced from the V-I measurements are described. An evaluation of the activation energies for electrical conductance showed that BZA decreased the activation/ Born energies for ionic conduction of tethered lipid membranes. It is concluded that BZA increased the average pore radius of the tBLM.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Springer Nature
dc.relation.ispartof	J Membr Biol
dc.relation.isbasedon	10.1007/s00232-023-00291-z
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0601 Biochemistry and Cell Biology, 0605 Microbiology, 1108 Medical Microbiology
dc.subject.classification	Physiology
dc.subject.classification	3101 Biochemistry and cell biology
dc.subject.mesh	Lipid Bilayers
dc.subject.mesh	Benzyl Alcohol
dc.subject.mesh	Benzyl Alcohol
dc.subject.mesh	Lipid Bilayers
dc.subject.mesh	Lipid Bilayers
dc.subject.mesh	Benzyl Alcohol
dc.title	The Effect of Benzyl Alcohol on the Voltage-Current Characteristics of Tethered Lipid Bilayers.
dc.type	Journal Article
utslib.citation.volume	256
utslib.location.activity	United States
utslib.for	0601 Biochemistry and Cell Biology
utslib.for	0605 Microbiology
utslib.for	1108 Medical Microbiology
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	closed_access	*
dc.date.updated	2024-01-16T00:29:59Z
pubs.issue	4-6
pubs.publication-status	Published
pubs.volume	256
utslib.citation.issue	4-6

Abstract:

In this study a lipid bilayer membrane model was used in which the bilayer is tethered to a solid substrate with molecular tethers. Voltage-current (V-I) measurements of the tethered bilayer membranes (tBLM) and tBLM with benzyl alcohol (BZA) incorporated in their structures, were measured using triangular voltage ramps of 0-500 mV. The temperature dependence of the conductance deduced from the V-I measurements are described. An evaluation of the activation energies for electrical conductance showed that BZA decreased the activation/ Born energies for ionic conduction of tethered lipid membranes. It is concluded that BZA increased the average pore radius of the tBLM.

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http://hdl.handle.net/10453/174515