Advanced triboelectric nanogenerator-driven drug delivery systems for targeted therapies.

Ikram, M; Mahmud, MAP

Advanced triboelectric nanogenerator-driven drug delivery systems for targeted therapies.

Ikram, M Mahmud, MAP

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Publisher:: SPRINGER HEIDELBERG
Publication Type:: Journal Article
Citation:: Drug Deliv Transl Res, 2023, 13, (1), pp. 54-78
Issue Date:: 2023-01

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Field	Value	Language
dc.contributor.author	Ikram, M
dc.contributor.author	Mahmud, MAP
dc.date.accessioned	2024-02-12T23:36:25Z
dc.date.available	2022-05-12
dc.date.available	2024-02-12T23:36:25Z
dc.date.issued	2023-01
dc.identifier.citation	Drug Deliv Transl Res, 2023, 13, (1), pp. 54-78
dc.identifier.issn	2190-393X
dc.identifier.issn	2190-3948
dc.identifier.uri	http://hdl.handle.net/10453/175607
dc.description.abstract	In the current decade, remarkable efforts have been made to develop a self-regulated, on-demand and controlled release drug delivery system driven by triboelectric nanogenerators (TENGs). TENGs have great potential to convert biomechanical energy into electricity and are suitable candidates for self-powered drug delivery systems (DDSs) with exciting features such as small size, easy fabrication, biocompatible, high power output and economical. This review exclusively explains the development and implementation process of TENG-mediated, self-regulated, on-demand and targeted DDSs. It also highlights the recently used TENG-driven DDSs for cancer therapy, infected wounds healing, tissue regeneration and many other chronic disorders. Moreover, it summarises the crucial challenges that are needed to be addressed for their universal applications. Finally, a roadmap to advance the TENG-based drug delivery system developments is depicted for the targeted therapies and personalised healthcare.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	SPRINGER HEIDELBERG
dc.relation.ispartof	Drug Deliv Transl Res
dc.relation.isbasedon	10.1007/s13346-022-01184-9
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1115 Pharmacology and Pharmaceutical Sciences
dc.subject.classification	3214 Pharmacology and pharmaceutical sciences
dc.subject.mesh	Humans
dc.subject.mesh	Drug Delivery Systems
dc.subject.mesh	Wound Healing
dc.subject.mesh	Wound Infection
dc.subject.mesh	Humans
dc.subject.mesh	Wound Infection
dc.subject.mesh	Drug Delivery Systems
dc.subject.mesh	Wound Healing
dc.subject.mesh	Humans
dc.subject.mesh	Drug Delivery Systems
dc.subject.mesh	Wound Healing
dc.subject.mesh	Wound Infection
dc.title	Advanced triboelectric nanogenerator-driven drug delivery systems for targeted therapies.
dc.type	Journal Article
utslib.citation.volume	13
utslib.location.activity	United States
utslib.for	1115 Pharmacology and Pharmaceutical Sciences
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Science
utslib.copyright.status	closed_access	*
dc.date.updated	2024-02-12T23:36:23Z
pubs.issue	1
pubs.publication-status	Published
pubs.volume	13
utslib.citation.issue	1

Abstract:

In the current decade, remarkable efforts have been made to develop a self-regulated, on-demand and controlled release drug delivery system driven by triboelectric nanogenerators (TENGs). TENGs have great potential to convert biomechanical energy into electricity and are suitable candidates for self-powered drug delivery systems (DDSs) with exciting features such as small size, easy fabrication, biocompatible, high power output and economical. This review exclusively explains the development and implementation process of TENG-mediated, self-regulated, on-demand and targeted DDSs. It also highlights the recently used TENG-driven DDSs for cancer therapy, infected wounds healing, tissue regeneration and many other chronic disorders. Moreover, it summarises the crucial challenges that are needed to be addressed for their universal applications. Finally, a roadmap to advance the TENG-based drug delivery system developments is depicted for the targeted therapies and personalised healthcare.

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http://hdl.handle.net/10453/175607