Synthesis of 2-acetyl-5-(1,2,3,4,5,6-hexahydroxyhexyl)thiazoles

Ung, AT; Pyne, SG; Jeoffreys, GR; Skelton, BW; White, AH

Synthesis of 2-acetyl-5-(1,2,3,4,5,6-hexahydroxyhexyl)thiazoles

Ung, AT

Pyne, SG Jeoffreys, GR Skelton, BW White, AH

Permalink

Publication Type:: Journal Article
Citation:: Monatshefte fur Chemie, 2011, 142 (3), pp. 297 - 303
Issue Date:: 2011-03-01

Closed Access

	Filename	Description	Size
	2010000151OK.pdf		513.34 kB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Ung, AT https://orcid.org/0000-0002-5665-0702	en_US
dc.contributor.author	Pyne, SG	en_US
dc.contributor.author	Jeoffreys, GR	en_US
dc.contributor.author	Skelton, BW	en_US
dc.contributor.author	White, AH	en_US
dc.date.issued	2011-03-01	en_US
dc.identifier.citation	Monatshefte fur Chemie, 2011, 142 (3), pp. 297 - 303	en_US
dc.identifier.issn	0026-9247	en_US
dc.identifier.uri	http://hdl.handle.net/10453/18013
dc.description.abstract	The syntheses of two diastereoisomers of 2-acetyl-5-(1,2,3,4,5,6- hexahydroxyhexyl)thiazole are reported. The synthesis of these diastereoisomers involved the coupling of 5-metallated 2-(1,1-dimethoxyethyl)thiazole with a Weinreb amide derived from d-gluconolactone, followed by asymmetric reduction of the ketone thus prepared. The stereochemistries and structures of some key compounds were determined by single-crystal X-ray structural analysis. © 2011 Springer-Verlag.	en_US
dc.relation.ispartof	Monatshefte fur Chemie	en_US
dc.relation.isbasedon	10.1007/s00706-011-0448-z	en_US
dc.subject.classification	General Chemistry	en_US
dc.title	Synthesis of 2-acetyl-5-(1,2,3,4,5,6-hexahydroxyhexyl)thiazoles	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.citation.volume	142	en_US
utslib.for	030503 Organic Chemical Synthesis	en_US
utslib.for	03 Chemical Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CCET - Centre for Clean Energy Technology
utslib.copyright.status	closed_access
pubs.issue	3	en_US
pubs.publication-status	Published	en_US
pubs.volume	142	en_US

Abstract:

The syntheses of two diastereoisomers of 2-acetyl-5-(1,2,3,4,5,6- hexahydroxyhexyl)thiazole are reported. The synthesis of these diastereoisomers involved the coupling of 5-metallated 2-(1,1-dimethoxyethyl)thiazole with a Weinreb amide derived from d-gluconolactone, followed by asymmetric reduction of the ketone thus prepared. The stereochemistries and structures of some key compounds were determined by single-crystal X-ray structural analysis. © 2011 Springer-Verlag.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/18013