Global malaria vaccine research and community perception in Africa: a systematic review

Chutiyami, M; Bello, UM; Salihu, D

Global malaria vaccine research and community perception in Africa: a systematic review

Chutiyami, M

Bello, UM Salihu, D

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Publisher:: Oxford University Press (OUP)
Publication Type:: Journal Article
Citation:: European Journal of Public Health, 2024, 34, (Suppl 3), pp. ckae144.1080
Issue Date:: 2024-11-01

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Field	Value	Language
dc.contributor.author	Chutiyami, M https://orcid.org/0000-0002-7378-6302
dc.contributor.author	Bello, UM
dc.contributor.author	Salihu, D
dc.date.accessioned	2024-11-19T03:38:05Z
dc.date.available	2024-11-19T03:38:05Z
dc.date.issued	2024-11-01
dc.identifier.citation	European Journal of Public Health, 2024, 34, (Suppl 3), pp. ckae144.1080
dc.identifier.issn	1101-1262
dc.identifier.issn	1464-360X
dc.identifier.uri	http://hdl.handle.net/10453/181981
dc.description.abstract	<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Malaria vaccine is one of the critical areas in tropical health research, considering the success recorded in other vaccine-preventable diseases. This review provides an overview of global malaria vaccine research and systematically reviews community perception of the vaccine in Africa.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>A validated search was conducted to identify scientific literature on malaria vaccines in the Scopus database from 2005. Bibliometric indicators explored include publication/citation indices over time and the overall research themes using VOSviewer. A further in-depth search was undertaken in five databases to identify studies on community perception of malaria vaccine in Africa. Studies were screened, quality appraised, and narratively synthesized.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>6457 malaria-vaccine-related documents were found in 160 journals/sources from 189 countries/territories. There were 214,323 total citations, with 33.2 average citations per document and 167 documents’ h-index. The United States, United Kingdom and Australia combined produced more than 60% of the publication output. Six themes emerged from the global malaria vaccine research: Merozoite surface protein, characterization, trials, infant/children, traveler, and research/review. Twenty studies (n = 20) met the inclusion criteria for the systematic review. Overall perceptions of malaria vaccines varied in African communities (26.2-88.2%), in addition to higher willingness to accept the vaccines (32.3%-96.0%), poor knowledge/awareness (11%-60%) and misconceptions (19.2%-20.9%). Other issues identified include vaccine availability and logistics.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Malaria vaccine research and citations have increased considerably, mainly targeting vaccine development and safety/efficacy in Africa. African communities’ perceptions of the vaccine varied, with most of the population willing to accept the vaccine.</jats:p> </jats:sec> <jats:sec> <jats:title>Key messages</jats:title> <jats:p>• An increase in number of malaria vaccine research targeting vaccine development, and safety and efficacy in Africa.</jats:p> <jats:p>• Varried malaria vaccine perception in Africa, including willingness to accept the vaccine, awareness, misconceptions, availability and logistics.</jats:p> </jats:sec>
dc.language	en
dc.publisher	Oxford University Press (OUP)
dc.relation.ispartof	European Journal of Public Health
dc.relation.isbasedon	10.1093/eurpub/ckae144.1080
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1117 Public Health and Health Services
dc.subject.classification	Public Health
dc.subject.classification	4202 Epidemiology
dc.subject.classification	4203 Health services and systems
dc.subject.classification	4206 Public health
dc.title	Global malaria vaccine research and community perception in Africa: a systematic review
dc.type	Journal Article
utslib.citation.volume	34
utslib.for	1117 Public Health and Health Services
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/School of Nursing and Midwifery
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by-nc/4.0/
dc.date.updated	2024-11-19T03:38:04Z
pubs.issue	Suppl 3
pubs.publication-status	Published
pubs.volume	34
utslib.citation.issue	Suppl 3

Abstract:

Abstract Background Malaria vaccine is one of the critical areas in tropical health research, considering the success recorded in other vaccine-preventable diseases. This review provides an overview of global malaria vaccine research and systematically reviews community perception of the vaccine in Africa. Methods A validated search was conducted to identify scientific literature on malaria vaccines in the Scopus database from 2005. Bibliometric indicators explored include publication/citation indices over time and the overall research themes using VOSviewer. A further in-depth search was undertaken in five databases to identify studies on community perception of malaria vaccine in Africa. Studies were screened, quality appraised, and narratively synthesized. Results 6457 malaria-vaccine-related documents were found in 160 journals/sources from 189 countries/territories. There were 214,323 total citations, with 33.2 average citations per document and 167 documents’ h-index. The United States, United Kingdom and Australia combined produced more than 60% of the publication output. Six themes emerged from the global malaria vaccine research: Merozoite surface protein, characterization, trials, infant/children, traveler, and research/review. Twenty studies (n = 20) met the inclusion criteria for the systematic review. Overall perceptions of malaria vaccines varied in African communities (26.2-88.2%), in addition to higher willingness to accept the vaccines (32.3%-96.0%), poor knowledge/awareness (11%-60%) and misconceptions (19.2%-20.9%). Other issues identified include vaccine availability and logistics. Conclusions Malaria vaccine research and citations have increased considerably, mainly targeting vaccine development and safety/efficacy in Africa. African communities’ perceptions of the vaccine varied, with most of the population willing to accept the vaccine. Key messages • An increase in number of malaria vaccine research targeting vaccine development, and safety and efficacy in Africa. • Varried malaria vaccine perception in Africa, including willingness to accept the vaccine, awareness, misconceptions, availability and logistics.

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http://hdl.handle.net/10453/181981