Synthesis and inhibitory activities at mGluRs of 3-alkylated and N-alkylated cyclopentyl-glutamate analogues

Pergamon-Elsevier Science Ltd
Publication Type:
Journal Article
Tetrahedron, 2013, 69 (12), pp. 2577 - 2587
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The conformationally restricted glutamate analogues, 3-alkyl-1-amino-2-cyclopentene-1,3-dicarboxylates and N-alkylated analogues have been prepared in a regioselective and diastereoselective manner. From the biological studies of the 3-alkylated analogue
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