A generalized transducing phage for the murine pathogen Citrobacter rodentium

Publication Type:
Journal Article
Microbiology, 2007, 153 (9), pp. 2984 - 2988
Issue Date:
Filename Description Size
Thumbnail2012007786OK.pdf265.73 kB
Adobe PDF
Full metadata record
A virulent phage (φCR1) capable of generalized transduction in Citrobacter rodentium was isolated from the environment and characterized. C. rodentium is a natural pathogen of mice, causing transmissible murine colonic hyperplasia. Sequencing of its genome has recently been completed and will soon be fully annotated and published. C. rodentium is an important model organism for infections caused by the human pathogens enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC and EHEC). φCR1 uses a lipopolysaccharide receptor, has a genome size of approximately 300 kb, and is able to transduce a variety of markers. φCR1 is the first reported transducing phage for C. rodentium and will be a useful tool for functional genomic analysis of this important natural murine pathogen. © 2007 SGM.
Please use this identifier to cite or link to this item: