A generalized transducing phage for the murine pathogen Citrobacter rodentium

Petty, NK; Toribio, AL; Goulding, D; Foulds, I; Thomson, N; Dougan, G; Salmond, GPC

A generalized transducing phage for the murine pathogen Citrobacter rodentium

Petty, NK

Toribio, AL Goulding, D Foulds, I Thomson, N Dougan, G Salmond, GPC

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Publication Type:: Journal Article
Citation:: Microbiology, 2007, 153 (9), pp. 2984 - 2988
Issue Date:: 2007-09-01

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Field	Value	Language
dc.contributor.author	Petty, NK https://orcid.org/0000-0001-6528-9886	en_US
dc.contributor.author	Toribio, AL	en_US
dc.contributor.author	Goulding, D	en_US
dc.contributor.author	Foulds, I	en_US
dc.contributor.author	Thomson, N	en_US
dc.contributor.author	Dougan, G	en_US
dc.contributor.author	Salmond, GPC	en_US
dc.date.issued	2007-09-01	en_US
dc.identifier.citation	Microbiology, 2007, 153 (9), pp. 2984 - 2988	en_US
dc.identifier.issn	1350-0872	en_US
dc.identifier.uri	http://hdl.handle.net/10453/27806
dc.description.abstract	A virulent phage (φCR1) capable of generalized transduction in Citrobacter rodentium was isolated from the environment and characterized. C. rodentium is a natural pathogen of mice, causing transmissible murine colonic hyperplasia. Sequencing of its genome has recently been completed and will soon be fully annotated and published. C. rodentium is an important model organism for infections caused by the human pathogens enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC and EHEC). φCR1 uses a lipopolysaccharide receptor, has a genome size of approximately 300 kb, and is able to transduce a variety of markers. φCR1 is the first reported transducing phage for C. rodentium and will be a useful tool for functional genomic analysis of this important natural murine pathogen. © 2007 SGM.	en_US
dc.relation.ispartof	Microbiology	en_US
dc.relation.isbasedon	10.1099/mic.0.2007/008888-0	en_US
dc.subject.classification	Microbiology	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Mice	en_US
dc.subject.mesh	Citrobacter rodentium	en_US
dc.subject.mesh	Myoviridae	en_US
dc.subject.mesh	Bacteriophages	en_US
dc.subject.mesh	DNA Transposable Elements	en_US
dc.subject.mesh	DNA, Viral	en_US
dc.subject.mesh	Microscopy, Electron	en_US
dc.subject.mesh	Electrophoresis, Gel, Pulsed-Field	en_US
dc.subject.mesh	Transduction, Genetic	en_US
dc.subject.mesh	Sewage	en_US
dc.title	A generalized transducing phage for the murine pathogen Citrobacter rodentium	en_US
dc.type	Journal Article
utslib.citation.volume	9	en_US
utslib.citation.volume	153	en_US
utslib.for	0605 Microbiology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - ithree - Institute of Infection, Immunity and Innovation
utslib.copyright.status	closed_access
pubs.issue	9	en_US
pubs.publication-status	Published	en_US
pubs.volume	153	en_US

Abstract:

A virulent phage (φCR1) capable of generalized transduction in Citrobacter rodentium was isolated from the environment and characterized. C. rodentium is a natural pathogen of mice, causing transmissible murine colonic hyperplasia. Sequencing of its genome has recently been completed and will soon be fully annotated and published. C. rodentium is an important model organism for infections caused by the human pathogens enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC and EHEC). φCR1 uses a lipopolysaccharide receptor, has a genome size of approximately 300 kb, and is able to transduce a variety of markers. φCR1 is the first reported transducing phage for C. rodentium and will be a useful tool for functional genomic analysis of this important natural murine pathogen. © 2007 SGM.

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http://hdl.handle.net/10453/27806