Subcompartmentalized Polymer Hydrogel Capsules with Selectively Degradable Carrier and Subunits

Publication Type:
Journal Article
Small, 2010, 6 (14), pp. 1558 - 1564
Issue Date:
Full metadata record
Files in This Item:
Filename Description Size
Thumbnail2013002741OK.pdf516.53 kB
Adobe PDF
Subcompartmentalized hydrogel capsules (SHCs) with selectively degradable carriers and subunits are designed for potential applications in drug delivery and microencapsulated biocatalysis. Thiolated poly(methacrylic acid) and poly(N-vinyl pyrrolidone) are used to assemble 3-µm-diameter carrier capsules and 300-nm-diameter subunits, independently stabilized by a diverse range of covalent linkages. This paper presents examples of SHCs with tens of subcompartments and their successful drug loading, as well as selective degradation of the SHC carrier and/or subunits in response to multiple chemical stimuli.
Please use this identifier to cite or link to this item: