The phosphoinositide 3 '-kinase p110 delta modulates contractile protein production and IL-6 release in human airway smooth muscle

Ge, Q; Moir, L; Trian, T; Niimi, K; Poniris, M; Shepherd, P; Black, J; Oliver, BG; Burgess, J

The phosphoinositide 3 '-kinase p110 delta modulates contractile protein production and IL-6 release in human airway smooth muscle

Ge, Q Moir, L Trian, T Niimi, K Poniris, M Shepherd, P Black, J Oliver, BG Burgess, J

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Publisher:: Wiley-Blackwell
Publication Type:: Journal Article
Citation:: Journal of Cellular Physiology, 2012, 227 (8), pp. 3044 - 3052
Issue Date:: 2012-01

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Full metadata record

Field	Value	Language
dc.contributor.author	Ge, Q	en_US
dc.contributor.author	Moir, L	en_US
dc.contributor.author	Trian, T	en_US
dc.contributor.author	Niimi, K	en_US
dc.contributor.author	Poniris, M	en_US
dc.contributor.author	Shepherd, P	en_US
dc.contributor.author	Black, J	en_US
dc.contributor.author	Oliver, BG	en_US
dc.contributor.author	Burgess, J	en_US
dc.date.issued	2012-01	en_US
dc.identifier.citation	Journal of Cellular Physiology, 2012, 227 (8), pp. 3044 - 3052	en_US
dc.identifier.issn	0021-9541	en_US
dc.identifier.uri	http://hdl.handle.net/10453/28531
dc.description.abstract	Transforming growth factor (TGF) beta 1 increases pro-inflammatory cytokines and contractile protein expression by human airway smooth muscle (ASM) cells, which could augment airway inflammation and hyperresponsiveness. Phosphoinositide 3' kinase (PI3K)	en_US
dc.publisher	Wiley-Blackwell	en_US
dc.relation.ispartof	Journal of Cellular Physiology	en_US
dc.relation.isbasedon	10.1002/jcp.23046	en_US
dc.subject.classification	Biochemistry & Molecular Biology	en_US
dc.subject.mesh	Muscle, Smooth	en_US
dc.subject.mesh	Lung	en_US
dc.subject.mesh	Cells, Cultured	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Asthma	en_US
dc.subject.mesh	Pulmonary Disease, Chronic Obstructive	en_US
dc.subject.mesh	Benzamides	en_US
dc.subject.mesh	Dioxoles	en_US
dc.subject.mesh	Morpholines	en_US
dc.subject.mesh	Chromones	en_US
dc.subject.mesh	Adenine	en_US
dc.subject.mesh	Quinazolines	en_US
dc.subject.mesh	Contractile Proteins	en_US
dc.subject.mesh	Interleukin-6	en_US
dc.subject.mesh	Gene Expression Regulation	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Aged	en_US
dc.subject.mesh	Aged, 80 and over	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	Tissue Donors	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.subject.mesh	Transforming Growth Factor beta1	en_US
dc.subject.mesh	Phosphatidylinositol 3-Kinases	en_US
dc.subject.mesh	Class I Phosphatidylinositol 3-Kinases	en_US
dc.title	The phosphoinositide 3 '-kinase p110 delta modulates contractile protein production and IL-6 release in human airway smooth muscle	en_US
dc.type	Journal Article
utslib.citation.volume	8	en_US
utslib.citation.volume	227	en_US
utslib.for	1116 Medical Physiology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
utslib.copyright.status	closed_access
pubs.declined	1970-01-01T00:00:00.0+1000
pubs.consider-herdc	false	en_US
pubs.issue	8	en_US
pubs.volume	227	en_US

Abstract:

Transforming growth factor (TGF) beta 1 increases pro-inflammatory cytokines and contractile protein expression by human airway smooth muscle (ASM) cells, which could augment airway inflammation and hyperresponsiveness. Phosphoinositide 3' kinase (PI3K)

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/28531